| 肾移植患者环孢素A血药浓度监测的临床分析 |
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| 引用本文： | 王兰君,李国兴. 肾移植患者环孢素A血药浓度监测的临床分析[J]. 放射免疫学杂志, 2008, 21(4): 354-355 |
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| 作者姓名： | 王兰君 李国兴 |
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| 作者单位： | 新乡医学院第一附属医院,453100 |
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| 摘 要： | 目的：研究肾移植术后患者环孢素A（CsA）浓度与临床疗效之间的关系。方法：采用荧光偏振免疫法。结果：正常组分别与中毒组、排异组之间血药浓度有显著性差异。结论：环孢素A血药浓度监测必须结合临床，综合考虑各方面的因素，实现个体化给药。
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| 关 键 词： | 肾移植 环孢素A 血药浓度监测 荧光偏振免疫法 |
Clinical Study on the Monitoring of Blood Concentration of Cyclosporine A in Renal Transplant Recipients |
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| Wang Lanjun,Li Guoxing. Clinical Study on the Monitoring of Blood Concentration of Cyclosporine A in Renal Transplant Recipients[J]. Journal of Radioimmanology, 2008, 21(4): 354-355 |
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| Authors: | Wang Lanjun Li Guoxing |
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| Abstract: | Objective To study the relationship between the blood concentration of Cyclosporine A(CsA) and therapeutic efficacy in renal transplant recipients.Methods The serum concentrations of were determined dynamically with fluorescence polarization immunoassay in 33 patients.Results There were significant differences among the blood concentrations of Cyclosporin A in stable patients,patients with toxic manifestation and patients with rejection(P<0.01).Conclusion Cyclosporine A(CsA) blood concentration monitoring is useful for individualization of treatment. |
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| Keywords: | kidney transplantation cyclosporine A blood drug concentration monitoring FPIA |
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