薏苡仁的生殖系统和抗性器官肿瘤药理作用研究进展

薏苡仁能抑制孕酮、雌二醇、睾酮及皮质激素的生物合成和分泌,因此薏苡仁可能主要抑制甾体激素生物合成中的共同阶段。薏苡仁的抗生育作用也可能与抑制性激素生物合成有关。薏苡仁还能促进排卵和松弛子宫平滑肌以及治疗痛经。薏苡仁还有抗宫颈癌、卵巢癌、乳腺癌和前列腺癌作用。今后应该深入研究薏苡仁中的各种活性成分的药理作用,为临床更恰当应用薏苡仁、薏苡(仁)麸、薏苡(仁)壳提供科学依据。

Advances in studies on pharmacological effects of Coicis Semen against genital system and sex organic tumor

Coicis Semen inhibits the biosynthesis and secretion of progesterone,estradiol,testosterone,and corticosteroid,so it may mainly block the common stage in biosynthesis of steroid hormone.The sterile effect of Coicis Semen is probably related to biosynthesis inhibition of sex hormone.Coicis Semen induces ovulation,and inhibits uterine contraction,and treats dysmenorrhea.Coicis Semen has effects against cervical carcinoma,oophoroma,breast cancer,and prostate cancer.The pharmacological effects of various active components of Coicis Semen should be studied more profoundly,in order to provide the scientific basis for the appropriate use of Coicis Semen,Coicis Semen bran,and Coicis Semen hull in clinic.