甲壳素及其衍生物壳聚糖的药理作用和临床应用研究进展

甲壳素及其衍生物壳聚糖是一种用途很广的天然高分子化合物,具有无毒、生物相容性好、吸附功能强、生物可降解等优异性能。随着对新材料的研究开发,甲壳素和壳聚糖在医药和卫生材料方面的研究成果已得到实际应用,甚至已工业化生产。综述了甲壳素和壳聚糖抗菌、止血、促愈合、提高免疫的药理作用及其在医用敷料方面的应用。

Research of pharmacologic action and clinical application of chitin and its derivative chitosan

Chitin and its derivative chitosan are very versatile natural macromolecular polymer,with good properties such as nontoxicity,good biocompatibility,strong absorption,and biodegration.Along with the development of new materials,the research achievement of chitin and chitosan in medical and hygiene material region have been put into practical application,or achieved industrial production.This paper reviewed pharmacologic action of chitin and chitosan in antibacterial,hemostasis,promoting agglutination and elevating immunity,and it’s application in medical excipient.