榼藤藤茎醋酸乙酯部位化学成分的研究

目的对榼藤Entada phaseoloide藤茎醋酸乙酯部位的化学成分进行研究。方法综合运用硅胶、反相硅胶RPC18、SephadexLH-20等色谱法进行分离,NMR、MS等波谱学方法进行结构鉴定。结果从榼藤藤茎甲醇提取物的醋酸乙酯萃取部位中分离得到了11个化合物,通过波谱分析鉴定为表没食子儿茶素没食子酸酯(1)、表儿茶素没食子酸酯(2)、落新妇苷(3)、木犀草素(4)、(?)-表儿茶素(5)、甘草苷(6)、β-香树脂醇(7)和日耳曼醇(8)的混合物、没食子酸(9)、β-谷甾醇(10)、胡萝卜苷(11)。结论所有化合物均为首次从榼藤中分离得到,其中化合物1～9在榼藤子属植物首次报道。

Constituents from ethyl acetate extract from canes of Entada phaseoloides

Objective To study the chemical constituents from ethyl acetate extract from canes of Entada phaseoloides.Methods The compounds were separated and purified by column chromatography on silica gel,RP C18,and Sephadex LH-20,and were identified by MS and NMR.Results Eleven compounds were isolated from the ethyl acetate fraction in methanol extract from canes of E.phaseoloide,and their structures were elucidated as epi-gallocatechin gallate(1),epicatechin gallate(2),astilbin(3),luteolin(4),(?)-epicatechin(5),liquiritin(6),mixture of β-amyrin(7) and germanicol(8),gallic acid(9),β-sitosterol(10) and daucosterol(11).Conclusion Compounds 1—11 are isolated from this plant for the first time.Compounds 1—9 are firstly reported in the plants of Entada Adans.