复发性胰腺炎139例病因分析

目的 探讨急性胰腺炎反复发作的诱发因素及复发性胰腺炎的预后.方法 对昆明医学院第一附属医院消化内科收集的832例急性胰腺炎患者根据发作次数分为单发组和复发组,对两组的病史特点、临床表现及预后分别进行比较.结果 单发组693例(83.3%),复发组139例(16.7%),两组患者年龄比较差异无统计学意义(P>0.05);而在复发组中男性比例明显高于女性(P<0.01),年龄相对集中在31~59岁,通过单因素分析显示:饮酒、胆结石病史、胆囊切除术后、高脂血症病史、血清高三酰甘油及高脂饮食病史等与复发性急性胰腺炎(RAP)相关;逐步Logistic回归分析发现:胆囊切除术后及胆结石病史为急性胰腺炎反复发作的最有可能的潜在危险因素.结论 胆囊切除术及胆结石病史是急性胰腺炎反复发作的高危因素,饮酒、高脂血症病史及高脂饮食也是RAP不容忽视的危险因素.

Etiological analysis of recurrent acute pancreatitis in 139 cases

Objective To investigate the relative risk factor of recurrent acute pancreatitis and the prognosis of recurrent acute pancreatitis.Methods Eight hundred and thirty-two inpatients with acute pancreatitis in our hospital were divided into two groups,simple pancreatitis and recurrent pancreatitis.And the medical history,clinical characteristics and prognosis of the two groups were compared.Results Six hundred and ninety-three patients（83.3%） with simple pancreatitis and 139 patients（16.7%） with recurrent pancreatitis,and there was no significant difference in average age between the two groups（P〉0.05）.However,the latter group showed that its frequency of male patients was higher than female patients（P〈0.01） and age ranged from 31 to 59.By means of single-factor analysis,alcohol,hyperlipidemia,gallstone,cystectomy and hypertrglyceridemia,were associated with the recurrent acute pancreatitis.Cystectomy and gallstone maybe more possible risk factors of recurrent acute pancreatitis by step Logistic analysis.Conclusion Cystectomy and gallstone maybe the most important risk factors of recurrent acute pancreatitis.Meanwile,alcohol,hyperlipidemia and fat diet also can not be neglected risk factors of recurrent acute pancreatitis.