| 树突状细胞与生殖道黏膜免疫 |
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| 引用本文： | 李莉,黄丽丽. 树突状细胞与生殖道黏膜免疫[J]. 国外医学:妇产科学分册, 2011, 0(5): 402-406 |
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| 作者姓名： | 李莉 黄丽丽 |
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| 作者单位： | 浙江省肿瘤医院;浙江大学医学院附属妇产科医院; |
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| 摘 要： | 树突状细胞是机体内功能最强大的抗原提呈细胞,广泛分布于机体黏膜表面,在固有免疫应答和适应性免疫应答中发挥重要作用。女性生殖道黏膜免疫既涉及对外来病原体的免疫防御,又涉及到对同种异体的精子及半同种异体移植物（胚胎）的免疫耐受,必然具有特殊的免疫学机制。综述树突状细胞与生殖道黏膜免疫研究进展。
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| 关 键 词： | 树突细胞 生殖器,女（雌）性 免疫,黏膜 孕妇 免疫耐受 |
Mucosal Dendritic Cells in the Genital Tract Immuology |
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| LI Li,HUANG Li-li. Mucosal Dendritic Cells in the Genital Tract Immuology[J]. Foreign Medical Sciences(Obstet Gynecol Fascicle), 2011, 0(5): 402-406 |
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| Authors: | LI Li HUANG Li-li |
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| Affiliation: | LI Li,HUANG Li-li. Department of Gynecologic Oncology,Zhejiang Cancer Hospital,Hangzhou 310022,China(LI Li),Women's Hospital,School of Medicine,Zhejiang University,Hangzhou 310006,China(HUANG Li-li) |
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| Abstract: | Dendritic cells(DCs)are the most potent antigen-presenting cell(APC)and play important roles in innate immune defense as well as in adaptive immunity. The female genital tract is immunologically unique in its requirement for immunity against a wide array of pathogens and for tolerance the allogeneic sperm and the semi-allogeneic embryo. This review summarizes the latest advances in our understanding of DCs in the genital tract with respect to their subsets,lineage,and function. |
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| Keywords: | Dendritic cells Genitalia female Immunity mucosal Pregnant women Immune tolerance |
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