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小剂量hCG联合HMG对低促性腺激素性腺功能减退症不育患者卵巢刺激的疗效观察
引用本文:傅永伦,匡延平. 小剂量hCG联合HMG对低促性腺激素性腺功能减退症不育患者卵巢刺激的疗效观察[J]. 国外医学:妇产科学分册, 2011, 0(5): 465-467
作者姓名:傅永伦  匡延平
作者单位:上海交通大学医学院附属第九人民医院辅助生殖科;
摘    要:目的:探讨小剂量人绒毛膜促性腺激素(hCG)联合人绝经期促性腺激素(HMG)应用于低促性腺激素性腺功能减退症(HH)患者的卵巢刺激的可行性及其疗效。方法:对5例HH患者采用50IUhCG联合HMG进行卵巢刺激,应用阴道超声、测量血清性激素等方法监测卵泡生长发育。结果:4例患者进行了诱发排卵6个周期,平均排卵(2.6±1.5)个,诱发排卵成功率100%,累积妊娠率100%。无患者改行多余卵泡穿刺术或体外受精-胚胎移植术,未发生中、重度卵巢过度刺激综合征,未发生高序多胎妊娠;均分娩单胎健康婴儿。1例患者进行控制性超排卵1个周期,穿刺7个卵泡,获卵5个,受精3个,分裂形成2个优质胚胎,胚胎移植后妊娠,足月分娩1个健康新生儿。结论:小剂量hCG联合HMG能够安全、有效地应用于HH患者的卵巢刺激,改善卵巢刺激的结局。

关 键 词:性腺功能减退症  绒毛膜促性腺激素  不育,女(雌)性  卵泡刺激素

Effect of Ovarian Stimulation with Low-Dose hCG Combined with HMG on Infertility Patients with Hypogonadotropic Hypogonadism
FU Yong-lun,KUANG Yan-ping. Effect of Ovarian Stimulation with Low-Dose hCG Combined with HMG on Infertility Patients with Hypogonadotropic Hypogonadism[J]. Foreign Medical Sciences(Obstet Gynecol Fascicle), 2011, 0(5): 465-467
Authors:FU Yong-lun  KUANG Yan-ping
Affiliation:. Department of Assisted Reproduction,9th People′s Hospital,School of Medicine,Jiaotong University,Shanghai 200011,China
Abstract:Objective:To investigate the effect of ovarian stimulation with low-dose hCG combined with HMG on infertility patients with hypogonadotropic hypogonadism. Mehtods:Five infertility patients with hypogonadotropic hypogonadism were undergone ovarian stimulation with 50 IU hCG combined with HMG. Vaginal ultrasound-B,serum sexual hormone were used to monitor determine follicular development. Results:Four infertility patients with hypogonadotropic hypogonadism were undergone ovulation induction with six cycles,th...
Keywords:Hypogonadism  Chorionic gonadotropin  Infertility  female  Follicle stimulating hormone  
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