儿童过敏性紫癜104例临床分析

目的 探讨儿童过敏性紫癜的临床特点.方法 对104例过敏性紫癜患儿的发病特点、临床表现、肾损害相关因素及预后等方面进行回顾性分析.结果 发病季节：第1、2、3、4季度的发病率依次为31.7%、26.8%、11.5%、30.7%;诱因：感染38例（36.5%）,食物过敏10例（9.6%）,肾损害者32例（31.0%）,其中单纯皮肤型、皮肤＋腹型、皮肤＋关节型、皮肤＋关节＋腹型患儿肾损害发生率分别为16.2%、38.3%、41.5%、67.2%.结论 过敏性紫癜发病率以1、2、3季度发病人数较多;发病诱因以感染为第1位;过敏性紫癜早期出现较多肾外症状者,易发生肾损害;以腹痛为首发症状的过敏性紫癜易误诊为急腹症.

Clinical analysis of 104 children with henoch-schonlein purpura

Objective To study the clinical characteristics of henoch - schonlein purpura （HSP）. Methods 104 HSP were retrospectively studied and patterns of onset, clinical manifestations, correlated factors of renal damage and outcomes were analysed. Results Seasons and onset：the percentage of the 1,2,3,4 quarter were 31.7% ,26.8%, 11.5% ,30.7%. Inducements： they were infections （38 cases ,36.5% ） ,allergic food （ 10 cases,9.6% ） ,totauy （ 32 cases ,31.0% ） presen- ted symptoms of renal damage. The percentages of patients presenting renal damage were 16.2% ,38.3% ,41.5% ,67.2% for the patients with purpura only, with purpura and joint symptoms, with purpura and gastrointestinal tract symptoms, with all the above symptoms respectively（P 〈 0. O1 ）. Conclusion Morbidity of HSP is more in the first, second and the third quarter. The most important inducing factor is infection. HSP patients with many extrarenal symptoms during earlyphase are prone to kidney damage. HSP patients whose first symptom is abdominal pain can be misdiagnosed as acute abdominal disease.