西酞普兰治疗脑卒中后肩手综合征并发抑郁的疗效分析

目的 探讨西酞普兰治疗脑卒中后肩手综合征并发抑郁的疗效及其对患侧上肢功能恢复的作用.方法 将155例脑卒中后肩手综合征并发抑郁患者随机分为治疗组与对照组,常规治疗相同,治疗组采用西酞普兰治疗,对照组采用多塞平治疗,治疗前后采用汉密顿抑郁量表（HAMD）、抑郁自评量表（SDS）记录精神状态,用Fugl-Meyer量表和目测类比评分法（VHS）对患者上肢关节被动运动范围、上肢和腕关节的运动功能、疼痛及水肿程度进行疗效对比.结果 经治疗28 d后两组比较,HAMD、SDS评分及减分率比较差异有统计学意义（P＆lt;0.05）,抑郁的治愈率、显效率、有效率及患者上肢功能的恢复比较差异均有统计学意义（P＆lt;0.05）.结论 西酞普兰治疗脑卒中并发抑郁患者具有较好的疗效.

The efficacy analysis of citalopram in the treatment of post-stroke depression in shoulder-hand syndrome

Objective To explore the efficacy of citalopram in the treatment of post - stroke depression in shoul - der - hand syndrome and its effect on the recovery of limb function. Methods 155 patients with post - stroke depression in shoulder- hand syndrome were randomly divided into treatment and control groups. Both groups were applied conventional therapy. The treatment group were administered citalopram, while doxepin served as control group. Hamilton depression rating ,scale（HAMD） and the self- rating depression scale （SDS） were used to scale spiritual status before and after treatment. Fugl - Meyer scale and visual analogue scale（VHS） were used to measure the passive movemerit of upper limb joint, the motor function of wrist and upper exremity and the degree of pain and edema, and thcirefficacy was compared. Results After 28 days, treatment, the difference of HAMD, SDS scores and reduction ratewere statistically significant （P 〈 0. 05 ）. The cure rate, exellent cure rate, and the resumption of upper extremity function in patients were statistically significant difference （ P 〈 0. 05）. Conclusion Citalopram has a good effect in the treatment of depression in stroke patients.