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Role of protease activated receptor-2 in lymph node metastasis of uterine cervical cancers
Authors:Israt Jahan  Jiro Fujimoto  Syed Mahfuzul Alam  Eriko Sato  Teruhiko Tamaya
Affiliation:(1) Department of Obstetrics and Gynecology, Gifu University School of Medicine, 1-1 Yanagido, 501-1194 Gifu City, Japan
Abstract:

Background  

Protease activated receptor-2 (PAR-2) has been implicated in cellular proliferation, invasion and metastasis in various tumors. Lymph node metastasis is an important patient prognostic factor for uterine cervical cancers. This prompted us to study the role of PAR-2 in lymph node metastasis of uterine cervical cancers.
Keywords:
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