神经内镜经单鼻蝶入路切除垂体腺瘤

目的：探讨神经内镜单鼻腔蝶窦入路在切除垂体腺瘤中的临床应用。方法：采用德国Rudolf公司生产的直径为4 mm的0°和30°观察镜,经单鼻腔蝶窦入路,内镜下切除垂体腺瘤30例,其中泌乳素瘤12例,生长激素瘤2例,无功能腺瘤16例,微腺瘤1例,复发垂体腺瘤1例。结果：内镜下全切除肿瘤27例,近全切除肿瘤3例,术后2例一过性脑脊液鼻漏,1例术后瘤腔出血,术后13例内分泌化验恢复正常,术后3-8个月随访14例,1例复发。结论：神经内镜单鼻腔蝶窦入路切除垂体腺瘤是一种更微创,暴露更好,并发症更少的手术方法。

Neuroendoscopic Endonasal Transsphenoidal Surgery for Pituitary Adenomas

Objective：To investigate the clinic application of endoscopic endonasal transsphenoidal surgery for pituitary adenomas.Methods： We use endoscopic made in German Rudolf company dimeters 4 mm 0° and 30°.The study focuse 30 patients with pituitary adenomas,of 12 with prolactinomas 2 with growth hormone-secreting adenomas,16 had nonsecreting adenomas,1 had microadenomas,1 patient had recurrent adenoma.Results： 27 underwent total resection and 3 subtotal resection Among the 14 patients with hormone-secreting adenomas,13 got recovery on hormone level,2 had transient cerebrospinal rhinorrhea which recovered within one week postoperatively with 3 to 8 moths follow-up 14 patients.there was one recurred case.Conclusions ：Neuroendoscopic endonasal transsphenoidal surgery for pituitary adenomas can reduce the tissue trauma,improved visualization,more complete tumor removal,and reduce complications.