补肾活血、调理冲任法治疗子宫内膜异位症不孕的临床研究

目的:观察中医补肾活血、调理冲任法治疗子宫内膜异位症引起不孕的临床疗效及其作用机制。方法:60例子宫内膜异位症患者分为中药治疗组、西药对照组各30例,中药治疗组采用补肾活血、调理冲任法进行治疗,西药对照组采用米非司酮治疗,2个疗程后观察2组患者的临床疗效,检测血清CA125、EMAB水平等。结果:中药治疗组总有效率为96.67%,妊娠率为47%,西药对照组总有效率为76.67%,妊娠率为27%,2组比较差异有统计学意义(P0.05)。与西药对照组比较,中药治疗组治疗后EMAB阳性率、血清CA125水平明显降低,差异有统计学意义(P0.05)。结论:采用中医补肾活血、调理冲任法治疗子宫内膜异位症引起的不孕能显著改善临床症状,提高受孕率。

Clinical effect of therapy method of tonifying kidney and activating blood circulation,regulating Chong and Ren on infertility induced by endometriosis

Objective：To observe the clinical effect of therapy method of tonifying kidney and activating blood circulation, regulating Chong and Ren on infertility induced by endometriosis and its mechanism of action. Methods：60 patients were randomly divided into traditional Chinese medicine treatment group and Western medicine control group. 2 months after treatment,clinical effects of 2 groups were observed and levels of CA125,EMAB in serum were detected. Results：Total ef-fective rate and pregnancy rate were respectively 96.67% and 47%in treatment group while above indexes were 76.67%and 27%in control group（P〈0.05）. Compared with control group,positive rate of EMAB and serum CA125 level were signifi-cantly decreased in treatment group（P〈0.05）. Conclusion：Therapy method of tonifying kidney and activating blood circu-lation,regulating Chong and Ren could markedly improve clinical symptoms and elevate the pregnancy rate of patients.