国人脑顶内沟的三维形态及其不对称性

目的 以MRI及三维可视化方法探索国人脑顶内沟的类型及形态特征，以期为端脑顶叶功能研究及相关疾病诊治提供解剖学依据。 方法 选取107例正常右利手中国人,应用3.0T GE磁共振扫描仪进行扫描,获取高分辨率脑MRI数据。利用BrainVISA软件建立顶内沟的三维解剖模型,并对顶内沟的形态类型进行观察分析。结果 顶内沟有3种分段模式：连续型、两段型和三段型。不同分段之间的分隔脑回或表面可见，或埋藏于脑沟内部。左脑以连续型为主（56.07%），右脑以两段型为主（58.49%），且左右脑顶内沟形态具有显著不对称性（P＜0.01）。男性大脑顶内沟以两段型为主(53.17%)，女性大脑顶内沟以连续型为主(49.43%)，但男女性顶内沟形态无明显性别差异（P＞0.05）。 结论 顶内沟形态复杂，具有3种形态类型，并有明显的侧别差异。

Three-dimensional morphology and asymmetry of the intraparietal sulcus in Chinese brain

Objective The pattern and morphological features of the intraparietal sulcus(IPS) were explored on MRI in vivo using 3D visualization method,so as to provide anatomical basis for the brain function studies of the parietal lobe as well as the diagnosis and treatment of the related diseases. Methods Totally 107 right-handed Chinese subjects were selected and scanned to acquire high quality MR images of the brains using 3.0T high-resolution magnetic resonance imaging scanner. The 3D anatomical model of the IPS was reconstructed by BrainVISA, then the morphological patterns of the IPS were observed and analyzed. Results There were three types of the IPS: continuous type, two segments type and three segments type. The gyri which separate different segments were either visible on the brain surface or buried within the sulcus. In the left brain, the continuous type was in dominant(56.07%),while the two segments type was the most common type in the right brain(58.49%)，and the morphology of the IPS had significant asymmetries in both sides（P＜0.01）.The male brain was dominated by the two segments type(53.17%), and the female brain was dominated by the continuous type(49.43%), but it did not have significant gender asymmetry（P＞0.05）. Conclusion The morphology of the IPS is very complicated and it has three main types. There are obvious bilateral differences within the IPS.