真实世界鹿瓜多肽注射液治疗骨折的中医证候与节气分析

目的：通过对使用鹿瓜多肽注射液的骨折患者进行相关信息分析，了解该患者中医临床特征。方法：该研究以2003-2014年全国26家三甲医院信息系统（Hospital Information System，HIS）中使用鹿瓜多肽注射液治疗骨折的住院患者为研究对象，分析其一般信息、中医证候和发病节气。结果：45-64岁患者最多，占39.84%，其中18-44岁男性患者使用较多，占43.38%；45-64岁女性患者较多，占44.33%。入院与出院患者主证均为气滞血瘀证，分别占总人数的60.53%、53.08%；立夏和雨水两个节气入院患者最多，分别占总人数的5.26%、5.24%。结论：使用鹿瓜多肽注射液治疗骨折患者以中老年人居多，患者病证以气滞血瘀证居多，立夏、雨水入院患者居多。为临床骨折治疗时应中医辨证论治，顺应疾病本身特点及节气变化，辨证用药的特点提供理论基础。

Analysis on Traditional Chinese Medicine Syndrome and Solar Term of Cervus and Cucumis Polypeptide Injection among Fracture Patients in the RealWorld

This paper was aimed to understand the clinical features of traditional Chinese medicine (TCM) through the analysis of relevant information among fracture patients treated by the Cervus and Cucumis Polypeptide Injection (CCPI). The study was conducted among fracture patients treated by CCPI in the hospital information systems (HIS) among 26 national triple-A hospitals from 2003 to 2014. The general information, TCM syndrome and solar term of morbidity were analyzed. The results showed that the number of patients from 45-64 years old were the most, accounting for 39.84%. Among them, the number of male patients from 18-44 years old was the most, accounting for 43.38%; the number of female patients from 45-64 year old was the most, accounting for 44.33%. The main TCM syndrome of admission and discharge was qi stagnation and blood stasis, which accounted for 60.53% and 53.08% , respectively. Beginning of Summer (7th solar term) and Rain Water (2nd solar term) were solar terms with the most patients, which accounted for 5.26% and 5.24%, respectively. It was concluded that the majority of fractures patients treated with CCPI were the elderly. The syndrome of qi stagnation and blood stasis was the most. The hospital admission of most patients was at the Beginning of Summer and Rain Water. It provided theoretical basis to pay attention on TCM syndrome differentiation in the treatment of clinical fractures. The treatment should be adapted to the characteristics of the disease itself, the change of solar terms, and dialectical medication.