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高强度聚焦超声对体外培养人肝癌细胞的作用
引用本文:王琳,杨爱珍,梁凤萍,陈惠英,秦叔逵. 高强度聚焦超声对体外培养人肝癌细胞的作用[J]. 临床肿瘤学杂志, 2004, 9(2): 149-151,154
作者姓名:王琳  杨爱珍  梁凤萍  陈惠英  秦叔逵
作者单位:210002,南京,解放军八一医院全军肿瘤中心内科;200000,上海爱申科技发展有限公司
摘    要:目的:探讨高强度聚焦超声的不同照射剂量对体外培养人肝癌细胞的作用。方法:观察人肝癌细胞经受不同剂量的高强度聚焦超声照射后的温度变化、死亡率、形态变化及其生长曲线。结果:随着高强度聚焦超声照射剂量增大,温度增加,其生物学效应越明显。结论:高强度聚焦超声能够杀灭肿瘤细胞,肿瘤细胞的死亡率与治疗剂量呈正相关。

关 键 词:高强度聚焦超声  肿瘤细胞  SMMC-7721细胞株
文章编号:1009-0460(2004)02-0149-04

The effect of HIFU on human hepatocarcinoma cell line in vitro
WANG Lin,YANG Ai-zhen,LIANG Feng-ping,et al.. The effect of HIFU on human hepatocarcinoma cell line in vitro[J]. Chinese Clinical Oncology, 2004, 9(2): 149-151,154
Authors:WANG Lin  YANG Ai-zhen  LIANG Feng-ping  et al.
Affiliation:WANG Lin,YANG Ai-zhen,LIANG Feng-ping,et al.The Oncology Center of PLA,No.81 Hospital,Nanjing 210002
Abstract:Objective:To evaluate the effects of different radio dosage of HIFU on hepatocarcinoma cells cultured in vitro.Methods:Observe the variability of temperature and morphology,the mortality and the growth curve of human hepatocarcinoma cell line SMMC-7721 administrated by different radio dosage of HIFU.Results:The more of the radio dosage of HIFU,the higher of the cell temperature and the more effectiveness of biological response.Conclusion:HIFU can kill human carcinoma cells and there is positive correlationship between the mortality of carcinoma cells and the radio dosage.
Keywords:HIFU  Carcinoma cells  SMMC-7721 cell line
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