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妊娠期妇女凝血指标变化的临床意义
引用本文:林向华,梁穆兴,段朝晖,黄松音,范侠. 妊娠期妇女凝血指标变化的临床意义[J]. 血栓与止血学, 2003, 9(1): 21-22
作者姓名:林向华  梁穆兴  段朝晖  黄松音  范侠
作者单位:中山大学附属第二医院检验科,广州,510120
摘    要:目的:探讨妊娠期妇女凝血指标变化的临床意义。方法:用法国STAGO compact全自动凝血分析仪对39例正常对照、76例中孕组(孕20~28周)及54例晚孕组(孕37~40周)妇女的凝血酶原时间(PT)、活化部分凝血酶时间(APTT)、纤维蛋白原(Fbg)、凝血酶时间(TT)进行检测。结果:中孕组、晚孕组与正常对照组相比,APTT及TT缩短,Fbg水平升高,差别均有非常显著性意义(P<0.01),PT无统计学差异(P<0.05);晚孕期与中孕期相比,PT和APTT有所延长,存在显著性差异(P<0.05)。结论:妊娠期妇女凝血功能有增强的趋势,机体呈现高凝状态,可能有利于产后快速有效止血。

关 键 词:妊娠期妇女 凝血指标变化 临床意义 凝血酶原时间 活化部分凝血酶时间 纤维蛋白原 凝血酶时间
文章编号:1009-6213(2003)01-0021-02
修稿时间:2002-10-12

Study on the Variation of Coagulation Indexes in Pregnancy
UN Xiang-hua,LIANG Mux-ing,DUAN Zhao-hui,HUANG Song-yin FAN Xia. Study on the Variation of Coagulation Indexes in Pregnancy[J]. Chinese Journal of Thrombosis and Hemostasis, 2003, 9(1): 21-22
Authors:UN Xiang-hua  LIANG Mux-ing  DUAN Zhao-hui  HUANG Song-yin FAN Xia
Affiliation:UN Xiang-hua,LIANG Mux-ing,DUAN Zhao-hui,HUANG Song-yin FAN XiaDepartment of Laboratory,the Second Affiliated Hospital,Sun Yat-Sen University,Guangzhou,510120
Abstract:Objective: To investigate the level and clinical significance of coagulation indexes in pregnancy. Methods: Prothrombin time(PT) , activated partial thromboplastin time(APTT), fibrinogen(Fbg) and thrombin time (IT) were determined in both normal group, pregnancies at middle stage and late stage, and analyze the correlation between them. Results: APTT and TT were shorten while Fbg increases obviously(P < 0.01), there was no significant difference between pregnancy and normal group in PT(P>0.05) . PT and APTT of the late pregnancies were a little longer than the middle stage(P<0.05) . Conclusion: There is a hypercoagulability state in pregnancy.
Keywords:Pregnancy Prothrombin time Activated partial thromboplastin time Fibrinogen Thrombin time
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