| 牙周炎治疗后龈沟液中弹性蛋白酶水平的变化 |
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| 引用本文： | 和璐,曹采方,沙月琴. 牙周炎治疗后龈沟液中弹性蛋白酶水平的变化[J]. 中华口腔医学杂志, 2000, 35(1): 15-17 |
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| 作者姓名： | 和璐 曹采方 沙月琴 |
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| 作者单位： | 北京医科大学口腔医学院牙周科,100081 |
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| 摘 要： | 目的 观察龈沟液中细胞外弹性蛋白酶和细胞内弹性蛋白酶在牙周基础治疗后的变化。方法用滤 要的袋内取样法取８例患者４３个牙位治疗前后的ＧＣＦ样本,以底物检测法测定其中的ＥＡ－Ｓ及ＥＡ－Ｐ水平。结果 治疗后的ＧＣＦ－ＥＡ－Ｓ、ＥＡ－Ｐ总量及ＥＡ－Ｓ浓度、ＥＡ－Ｓ／ＥＡ／Ｐ比值均较治疗前师表ＥＡ－Ｐ浓度治疗前后无显著差异。结论ＧＣＦ－ＥＡ水平反映牙周组织的炎症破坏程度,可作为评价疗效的客观指标,尤其是ＥＡ
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| 关 键 词： | 牙周炎 龋沟液 弹性蛋白酶 |
| 修稿时间： | :1999-01-2 |
Changes of elastase in gingival crevicular fluid after periodontal treatment of adult periodontitis patients |
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| HE Lu,CAO Caifang,SHA Yueqin. Changes of elastase in gingival crevicular fluid after periodontal treatment of adult periodontitis patients[J]. Chinese journal of stomatology, 2000, 35(1): 15-17 |
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| Authors: | HE Lu CAO Caifang SHA Yueqin |
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| Affiliation: | HE Lu(Department of Periodontology,School of Stomatology,Beijing Medical University,Beijing100081,China)CAO Caifang(Department of Periodontology,School of Stomatology,Beijing Medical University,Beijing100081,China)SHA Yueqin(Department of Periodontology,School of Stomatology,Beijing Medical University,Beijing100081,China) |
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| Abstract: | Objective To examine the changes of elastase in the supernatant (EA s) and in the pellet (EA p) after centrifuge in gingival crevicular fluid(GCF) before and after periodontal treatment Methods GCF was sampled with filter paper strips by intra pocket method to determine EA levels Forty three teeth of eight subjects were included EA s and EA p were determined seperately using the subtract Meosuc ala ala val pro NA Results EA s per site and per ml, EA p per site and the ratio of EA s/EA p(S/P) decreased significantly after non surgical periodontal treatment ( P < 0 001), while EA p concentration didn't change( P > 0 05) Conclusions GCF EA s and EA p could act as objective parameters to evaluate the effect of periodontal therapy, especially EA s and S/P, which may be sensitive diagnostic parameters for determining periodontal disease activity |
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| Keywords: | Periodontitis Pancreatopeptidase Gingival crevicular fluid |
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