| 氯沙坦逆转高血压左室肥厚的临床研究(附50例报告) |
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| 引用本文： | 阳军,李敬东,孙华保. 氯沙坦逆转高血压左室肥厚的临床研究(附50例报告)[J]. 河北医科大学学报, 2004, 25(1): 15-17 |
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| 作者姓名： | 阳军 李敬东 孙华保 |
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| 作者单位： | 广东医学院附属湛江中心人民医院心内科,广东,湛江,524037;广东医学院附属湛江中心人民医院心内科,广东,湛江,524037;广东医学院附属湛江中心人民医院心内科,广东,湛江,524037 |
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| 摘 要： | 目的探讨氯沙坦对高血压左室肥厚的逆转作用。方法观察 5 0例高血压左室肥厚患者口服氯沙坦2 4周后左室形态结构和左室功能变化。结果治疗 8周后血压下降明显 ,治疗 2 4周后超声心动图显示室间隔、左室后壁肥厚明显减退 ,左室质量指数下降 ,总有效率达 85 .0 %。结论氯沙坦在降压的同时具有逆转高血压左室肥厚的作用。
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| 关 键 词： | 氯沙坦 高血压 肥大 左心室 |
| 文章编号： | 1007-3205(2004)01-0015-03 |
| 修稿时间： | 2003-01-03 |
CLINICAL STUDY OF LOSARTAN ON REVERSION OF LEFT VENTRICULAR HYPERTROPHY IN 50 PATIENTS WITH HYPERTENSION |
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| YANG Jun,LI Jing-dong,SUN Hua-bao. CLINICAL STUDY OF LOSARTAN ON REVERSION OF LEFT VENTRICULAR HYPERTROPHY IN 50 PATIENTS WITH HYPERTENSION[J]. Journal of Hebei Medical University, 2004, 25(1): 15-17 |
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| Authors: | YANG Jun LI Jing-dong SUN Hua-bao |
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| Abstract: | ObjectiveTo study the effects of losartan on reversion of left ventricular hypertrophy(LVH) in patients with hypertension.MethodsFifty patients with LVH were treated with losartan(50 mg/d) for 24 weeks,and then all the patients underwent echocardiography to monitor left ventricular structure and function changes.ResultsAfter 8 weeks treatment blood pressure was lowered significantly.After 24 weeks treatment interventricular septum diastolic thickness(IVST),left ventricular posterior wall thickness(LVPWT),left ventricular mass index(LVMI) decreased significantly(P< 0.01),respectively.The total effective ratio was 85.0 .ConclusionAccompanying antihypertension effects,losartan has effects on reversion of LVH in the patients with essential hypertension. |
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| Keywords: | losartan hypertention hypertrophy left ventricular |
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