Aspergillosis of ethmoid sinus and optic nerve, with arteritis and rupture of the internal carotid artery |
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| Authors: | N Corvisier F Gray R Gherardi F Lebras C M Blanc J P Nguyen J Poirier |
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| Affiliation: | 1. Real Hospital Português de Beneficência, Recife, Pernambuco State, Brazil;2. Programa de Pós-Graduação em Biologia de Fungos, Universidade Federal de Pernambuco (UFPE), Pernambuco, Brazil;3. Departamento de Patologia e Medicina Legal, Universidade Federal do Ceará (UFC), Brazil;4. Département de Parasitologie et Mycologie Médicale, Université de Nantes, EA1155 - IICiMed UFR des Sciences Pharmaceutiques, Nantes, France;5. Departamento de Medicina Tropical, UFPE, Brazil;1. Department of Microbiology, Central Clinical Hospital in Warsaw, Warsaw, Poland;2. Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland;3. Department of Dental Microbiology, Medical University of Warsaw, Warsaw, Poland;1. Institute of Organ Transplantation, General Hospital of Chinese People''s Armed Police Force, Beijing, China;2. Department of Organ Transplantation, Tianjin First Central Hospital, Tianjin, China;1. Resident, Department of Microbiology, Armed Forces Medical College, Pune, India;2. Resident, Department of Oral Maxillo Facial Surgery, Armed Forces Medical College, Pune, India;3. Associate Professor, Department of Microbiology, Armed Forces Medical College, Pune, India;4. Professor & Head, Department of Microbiology, Armed Forces Medical College, Pune, India;5. Associate Professor, Department of Oral Maxillo Facial Surgery, Armed Forces Medical College, Pune, India |
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| Abstract: | A 54-year-old woman had been treated 26 years previously for Hodgkin's disease. Eight months before presentation, the disease had recurred and the patient had received cytotoxic drugs and steroids. She presented with loss of vision of the right eye and died 5 months later from extensive subarachnoid hemorrhage. Postmortem examination revealed an aspergillus abscess of the ethmoid sinus, extending to the right frontal lobe and optic nerve, and to the wall of the right internal carotid artery (ICA). Death was due to rupture of the ICA. Such a presentation of aspergillosis is unusual. Three cases of aspergillus arteritis causing rupture of the ICA have been reported previously. |
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