Intriguing issues of EGFR targeting in head and neck cancer |
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Authors: | Karamouzis MV; Konstantinopoulos PA; Papavassiliou AG |
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Institution: | 1 Department of Biological Chemistry, Medical School, University of Athens, Athens, Greece
2 Division of Hematology-Oncology, University of Pittsburgh, Pittsburgh
3 Division of Hematology-Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA |
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Abstract: | We have read the recent comprehensive review by Cruz et al.1] regarding the targeting of receptor tyrosine kinases andtheir therapeutic perspectives in head and neck squamous cellcarcinomas (HNSCC). The major focus of this report was epidermalgrowth factor receptor (EGFR) biology and targeting. However,we feel |
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