| 正清风痛宁与雷公藤总苷治疗IgA肾病疗效比较 |
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| 引用本文： | 蔡辉,梁萌,许树根,孙琪.正清风痛宁与雷公藤总苷治疗IgA肾病疗效比较[J].临床军医杂志,2008,36(5). |
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| 作者姓名： | 蔡辉 梁萌 许树根 孙琪 |
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| 作者单位： | 解放军第174医院,肾病中心,福建,厦门,361003 |
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| 摘 要： | 目的比较正清风痛宁与雷公藤总苷治疗IgA肾病的疗效。方法经肾穿刺活检并结合临床确诊为原发性IgA肾病53例,随机分成两组,对照组23例,服用雷公藤总苷;治疗组30例,服用正清风痛宁。结果对照组与治疗组在研究开始时各项指标间无统计学差异(P>0.05)。治疗3个月时,对照组与治疗组24h尿蛋白定量及尿RBC计数下降比值对比无统计学意义(P>0.05);但对照组副作用出现总频数为26%;而治疗组副作用出现总频数为10%。结论雷公藤总苷与正清风痛宁治疗IgAN,对于肾小球肾炎的蛋白尿及镜下血尿均有明显疗效,但正清风痛宁较雷公藤总苷副作用更少。
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| 关 键 词： | 正清风痛宁 雷公藤总苷片 IgA肾病 |
Comparison of Curative Effects on IgA Nephropathy between Zhengqing Fengtongning and Multi-glycosides of Tripterygii |
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| Cai Hai,Liang Meng,Xu Shu-gen,Sun Qi.Comparison of Curative Effects on IgA Nephropathy between Zhengqing Fengtongning and Multi-glycosides of Tripterygii[J].Clinical Journal of Medical Officer,2008,36(5). |
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| Authors: | Cai Hai Liang Meng Xu Shu-gen Sun Qi |
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| Institution: | Cai Hui,Liang Meng,Xu Shu-gen,Sun Qi(Center of Nephropathy,PLA No.174 Hospital,Xiamen 361003,China) |
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| Abstract: | Objective To compare the curative effects between Zhengqing Fengtongning and multi-glycosides of tripterygii on IgA nephropathy(mesangial proliferative glomerulonephritis,MPG).Methods A total of 53 patients with primary IgA nephropathy finally diagnosised by kidney biopsy and clinical characteristics were divided into two groups at random,i.e.trial group(n=30) treated with Zhengqing Fengtongning and control group(n=23) treated with multi-glycosides of tripterygii.The decreases in 24 hours urinary protein qu... |
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| Keywords: | zhengqing fengtongning multi-glycosides of tripterygii IgA nephropathy |
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