铁缺乏症婴幼儿认知水平研究

目的 了解非贫血铁缺乏症和缺铁性贫血婴幼儿的认知水平, 为进一步治疗提供科学依据。方法 采用Gesell发育测试法评估非贫血铁缺乏症和缺铁性贫血婴幼儿适应性、大运动、精细动作、语言和个人社交5个能区发育水平。结果 患铁缺乏症的男婴较女婴更多(χ²=13.06, P=0.001), 非贫血铁缺乏症(non-anemia iron deficiency, NAID)组、缺铁性贫血(iron deficiency anemia, IDA)组较铁充足(iron sufficiency, IS)组婴幼儿的5个能区发育水平落后(F_适应性=13.64;F_大运动=6.24;F_精细动作=6.25;F_语言=4.89;F_个人社交=9.14, P值均<0.01), NAID和IDA婴幼儿之间差异无统计学意义;但男性婴幼儿在语言和个人社交发育商分数较女婴更低(F=9.299, P=0.003;F=4.250, P=0.042)。结论 铁缺乏症伴或不伴贫血对婴幼儿的认知水平都有影响, 提示在临床工作中应早期干预铁缺乏。

Analysis of iron deficiency infants' cognitive level.

Objective To analyse the non-anemia iron deficiency(NAID) and iron deficiency anemia(IDA) infants' cognitive level. Method The Gesell developmental test was used to assess the development of adaptive behavior(A), gross motor(G), fine motor(F), language(L), personal-social behavior(P). Results Both NAID and IDA groups' male infants were more than female ones(χ²=13.06, P=0.001);The mental developmental quotient(DQ) of NAID group and IDA group was lower than iron sufficiency (IS) group, but no difference between NAID group and IDA group(FA=13.64, FG=6.24, FF=6.25, FL=4.89, FP=9.14, all P<0.01);The male infants' developmental quotients(DQ) of language, personal-social behavior were significantly lower than those of female infants(F=9.299, P=0.003;F=4.250, P=0.042). Conclusion The DQ of Iron deficiency with or without anemia infants are lower than iron sufficient ones, that means iron deficiency needs early intervention in clinic.