| 多发性骨髓瘤的18F-FDG PET/CT鉴别诊断及疗效评估价值 |
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| 引用本文： | 宋建华,赵晋华,陈香,邢岩,汪太松,乔文礼. 多发性骨髓瘤的18F-FDG PET/CT鉴别诊断及疗效评估价值[J]. 中国医学计算机成像杂志, 2011, 17(1) |
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| 作者姓名： | 宋建华 赵晋华 陈香 邢岩 汪太松 乔文礼 |
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| 作者单位： | 上海交通大学附属第一人民医院核医学科 |
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| 摘 要： | 目的:分析多发性骨髓瘤(M M)的18F-FDG PET/CT影像表现,探讨PET/CT对MM的鉴别诊断及疗效评估价值.方法:回顾性分析近3年来我院经病理证实的22例M M患者的PET/CT影像资料,包括男13例,女9例.其中5例有治疗后多次PET/CT随访影像资料.结果:22例均为多发骨病灶,合并病理骨折11例38处病灶.PET/CT表现为弥漫性或多发穿凿样骨破坏,骨破坏不明显时可仅表现为髓腔密度增高;少数骨病灶可有膨胀性表现,骨皮质穿破后可形成软组织肿块;全身骨病灶代谢不均匀增高,SUVmax=5.6±2.3;病理骨折处SUVmax=4.9±0.7;骨破坏区和代谢增高区可不一致;治疗后MM病灶代谢程度降低,PET所见变化早于CT形态变化;病理骨折处代谢增高,需和肿瘤活性残留相鉴别.结论:PET/CT有助于MM的鉴别诊断并早期评价病灶的疗效反应,具有重要临床应用价值.
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| 关 键 词： | 体层摄影术,发射型计算机 18F-氟代脱氧葡萄糖 多发性骨髓瘤 |
Differentiation and Curative Effect Evaluation of Multiple Myeloma with 18F-FDG PET/CT |
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| SONG Jian-hua,ZHAO Jin-hua,CHEN Xiang,XING Yan,WANG Tai-song,QIAO Wen-li. Differentiation and Curative Effect Evaluation of Multiple Myeloma with 18F-FDG PET/CT[J]. Chinese Computed Medical Imaging, 2011, 17(1) |
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| Authors: | SONG Jian-hua ZHAO Jin-hua CHEN Xiang XING Yan WANG Tai-song QIAO Wen-li |
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| Affiliation: | SONG Jian-hua,ZHAO Jin-hua,CHEN Xiang,XING Yan,WANG Tai-song,QIAO Wen-li Department of Nuclear Medicine,Shanghai First People's Hospital,Shanghai Jiaotong University100 Haining Rd.,Shanghai 200080,P.R.C |
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| Abstract: | Purpose: To explore the differential diagnostic value and the curative effect evaluation value for multiple myeloma with 18F-FDG PET/CT.Methods:Twenty-two cases of multiple myeloma which were examed with 18F-FDG PET/CT and confirmed by pathology in the last 3 years were retrospectively analyzed.There were 13 male and 9 female.Five of them had follow-up examinations with 18F-FDG PET/CT.Results: All of the cases had multiple lesions and 11 of them had 38 lesions combined with pathological fracture.PET/CT find... |
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| Keywords: | Tomography emission-computed 18F Fluorodeoxyglucose multiple myeloma |
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