| 替硝唑乳膏的制备及质量控制 |
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| 引用本文： | 匡长春,欧阳京,王志朝,刘祖雄. 替硝唑乳膏的制备及质量控制[J]. 中国药业, 2011, 20(4): 51-52 |
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| 作者姓名： | 匡长春 欧阳京 王志朝 刘祖雄 |
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| 作者单位： | 1. 中国人民解放军广州军区武汉总医院药剂科,湖北,武汉,430070
2. 中国人民解放军总参谋部军训和兵种部第二管理处门诊部药房,北京,100852 |
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| 摘 要： | 目的介绍替硝唑乳膏的制备及质量控制方法。方法以替硝唑为原料制备替硝唑乳膏,用紫外分光度法测定替硝唑的含量,并观察其稳定性。结果制剂中主药替硝唑的平均回收率为99.88%,RSD为0.28%(n=9)。结论该制剂稳定,制备工艺简单实用,质量控制方法可靠。
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| 关 键 词： | 替硝唑 乳膏 紫外分光度法 工艺 含量 |
Preparation and Quality Control of Tinidazole Cream |
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| Kuang Changchun,Ouyang Jing,Wang Zhichao,Liu Zuxiong. Preparation and Quality Control of Tinidazole Cream[J]. China Pharmaceuticals, 2011, 20(4): 51-52 |
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| Authors: | Kuang Changchun Ouyang Jing Wang Zhichao Liu Zuxiong |
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| Affiliation: | Kuang Changchun1,Ouyang Jing2,Wang Zhichao1,Liu Zuxiong1(1.Department of Pharmacy,Wuhan General Hospital of Guangzhou Military Region,Wuhan,Hubei,China 430070,2.Department of Pharmacy,Outpatient Clinic,Second Administrative Office,Department of Military Training and Army of the Services,Headquarters of General Staff,Beijing,China 100852) |
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| Abstract: | Objective To introduce the preparation and quality control method of Tinidazole Cream.Methods To prepare Tinidazole Cream with tinidazole as raw material and to measure the content of tinidazole directly by UV spectrophotometry.Its stable quality was observed.Results The average recovery rate of tinidazole was 99.88%,RSD=0.28%(n=9).Conclusion This preparation method is simple and the quality of products is stable.The product is suitable for the hospital preparation and application in clinic. |
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| Keywords: | Tinidazole cream UV spectrophotometry technology content |
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