| 高效液相色谱法测定骨刺消片中薯蓣皂苷含量 |
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| 引用本文： | 袁春筱,陈志新.高效液相色谱法测定骨刺消片中薯蓣皂苷含量[J].中国药业,2011,20(2):34-35. |
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| 作者姓名： | 袁春筱 陈志新 |
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| 作者单位： | 1. 重庆医科大学附属第二医院,重庆,400010
2. 中国人民解放军第6905工厂职工医院,重庆,400712 |
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| 摘 要： | 目的测定骨刺消片中薯蓣皂苷的的含量。方法采用高效液相色谱(HPLC)法。色谱柱为Symmetry C18柱(200 mm×4.6mm,5μm),以乙腈-水(26∶74)为流动相,检测波长为203 nm。结果薯蓣皂苷进样量在0.56～5.60μg范围内与峰面积呈良好线性关系(r=0.9999);平均回收率为98.24%,RSD为0.88%(n=6)。结论 HPLC法快速、准确,可用于该制剂的质量控制。
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| 关 键 词： | 薯蓣皂苷 骨刺消片 高效液相色谱法 |
Determination of Dioscin in Gucixiao Tablets by HPLC |
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| Yuan Chunxiao,Chen Zhixin.Determination of Dioscin in Gucixiao Tablets by HPLC[J].China Pharmaceuticals,2011,20(2):34-35. |
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| Authors: | Yuan Chunxiao Chen Zhixin |
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| Institution: | Yuan Chunxiao1,Chen Zhixin2(1.Second Affiliated Hospital,Chongqing Medical University,Chongqing,China 400 010,2.Staff Hospital,6905 Factory of PLA,China 400712) |
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| Abstract: | Objective To determine the contents of dioscin in Gucixiao Tablets.M ethods The HPLC method was adopted and the C18 column（200 mm×4.6 mm,5 μm） was used.The mobile phase was acetonitrile-water（26 ∶74）.The detection wavelength was at 203 nm.Results The calibration curve of dioscin was linear in the range o f 0.56-5.60 μg（r=0.999 9）.The average recovery rate was 98.24%,RSD was 0.88 %（n=6）.Conclusion HPLC is quick and accurate,which can be used for the quality control of Gucixiao Tablets. |
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| Keywords: | dioscin Gucixiao Tablets HPLC |
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