| 冠心生脉口服液质量标准研究 |
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| 引用本文： | 李海燕,康建. 冠心生脉口服液质量标准研究[J]. 中国药业, 2011, 20(1): 18-20 |
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| 作者姓名： | 李海燕 康建 |
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| 作者单位： | 1. 河南省食品药品检验所,河南,郑州,450003
2. 郑州大学第一附属医院,河南,郑州,450052 |
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| 摘 要： | 目的建立冠心生脉口服液的定性鉴别及含量测定方法。方法采用薄层色谱法定性鉴别冠心生脉口服液方中赤芍、麦冬、人参及三七、五味子;用高效液相色谱法测定赤芍中芍药苷的含量。结果薄层色谱的斑点清晰,分离度较好,阴性无干扰;芍药苷进样量在0.406 5～5.284 5μg范围内与峰面积线性关系良好,平均回收率为98.00%,RSD为1.37%(n=6)。结论所建立的定性定量方法可用于冠心生脉口服液的质量控制。
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| 关 键 词： | 冠心生脉口服液 薄层色谱法 赤芍 麦冬 人参 三七 五味子 芍药苷 高效液相色谱法 |
Study of Quality Standard on Guanxin Shengmai Oral Liquid |
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| Li Haiyan,Kang Jian. Study of Quality Standard on Guanxin Shengmai Oral Liquid[J]. China Pharmaceuticals, 2011, 20(1): 18-20 |
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| Authors: | Li Haiyan Kang Jian |
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| Affiliation: | Li Haiyan1,Kang Jian2(1.Henan Provincial Institute for Food and Drug Control,Zhengzhou,Henan,China 450003,2.First Affiliated Hospital,Zhengzhou University,China 450052) |
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| Abstract: | Objective To establish the methods of qualitative identification and content determination in Guanxin Shengmai Oral Liquid.Methods The TLC method was used to qualitatively identify Radix Paeoniae Rubra,Radix Ophiopogonis,Radix et Rhizoma Ginseng and Radix et Rhizoma Notoginseng,Fructus Schisandrae Chinensis,and the HPLC method was adopted to determine the content of peoniflorin.Results The spots of TLC were fairly clear with the good separation.The linear range of peoniflorin was 0.406 5-5.284 5 μg.The average recovery rate was 98.00%,RSD was 1.37%（n=6）.Conclusion The established standard is applicable for the quality control of Guanxin Shengmai Oral Liquid. |
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| Keywords: | Guanxin Shengmai Oral Liquid TLC Radix Paeoniae Rubra Radix Ophiopogonis Radix et Rhizoma Ginseng Radix et Rhizoma Notoginseng Fructus Schisandrae Chinensis paeoniflorin HPLC |
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