注射用帕米膦酸二钠致肌肉疼痛

1例75岁男性患者,因治疗前列腺癌骨转移,静脉滴注帕米膦酸二钠60mg+0.9%氯化钠注射液500mL。14d后出现左上臂肌肉疼痛,逐渐发展至右上臂、胸部肌肉疼痛,同时两手手指发僵。考虑帕米膦酸二钠致肌肉疼痛,遂给予口服萘汀美酮每次0.5g,每日2次,持续10d,肌肉疼痛症状缓解并逐渐消失。

Muscle pain caused by the iujectable pamidronate disodium

A 75-year-old male patient received an intravenous infusion of 60 mg pamidronate disodium,which was dissolved in 500 mL of 0.9% sodium chloride,for the treatment of bone metastasis by prostate cancer.Fourteen days later,the patient developed muscle pain of left upper arm and gradually developed into the right upper arm and chest muscle pain,while hands fingers stiffened.Nabumetone was orally given with the dose of 0.5 g each time,twice one day.Ten days later,the muscle pain symptoms relieved and disappeared...