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正交试验法优选三七止血贴中三七的提取工艺研究
引用本文:姚少毅,叶茂清,张潮林,廖华卫.正交试验法优选三七止血贴中三七的提取工艺研究[J].中国药业,2011,20(4):46-48.
作者姓名:姚少毅  叶茂清  张潮林  廖华卫
作者单位:1. 中山大学附属博济医院,广东,广州,511300
2. 广东省四会市人民医院,广东,肇庆,526200
3. 深圳万和制药有限公司,广东,深圳,518057
4. 广东药学院中药学院,广东,广州,510006
摘    要:目的 优选三七止血贴中三七药材的最佳提取工艺.方法 采用正交试验法,以提取液中人参皂苷Rg1、人参皂苷Rb1、三七皂苷R1的总含量为指标,优选药材的提取工艺.结果 药材较优的提取工艺为加70%的乙醇8倍,提取3次,每次0.5 h.结论 优选的提取工艺三七总皂苷提取率高,操作简便,适用于生产.

关 键 词:三七止血贴  正交试验法  人参皂苷Rg1  人参皂苷Rb1  三七皂苷R1

Study on Extraction Process of Radix Notojinseng in Sanqi Zhixue Patchs by Orthogonal Design
Yao Shaoyi,Ye Maoqing,Zhang Chaolin,Liao Huawei.Study on Extraction Process of Radix Notojinseng in Sanqi Zhixue Patchs by Orthogonal Design[J].China Pharmaceuticals,2011,20(4):46-48.
Authors:Yao Shaoyi  Ye Maoqing  Zhang Chaolin  Liao Huawei
Institution:Yao Shaoyi1,Ye Maoqing2,Zhang Chaolin3,Liao Huawei4(1.Affiliated Boji Hospital,Sun Yat-sen University,Guangzhou,Guangdong,China 511300,2.People's Hospital of Sihui City,Sihui,China 526200,3.Shenzhen Wanhe Pharmaceutical Co.,Ltd.,Shenzhen,China 518057,4.School of TCM,Guangdong Pharmaceutical College,China 510006)
Abstract:Objective To optimize the extraction technology of medicinal material radix notojinseng in Sanqi Zhixue Patchs.Methods The orthogonal test was employed for selecting the optimum extraction technology with the total contents of ginsenoside Rg1,ginsenoside Rb1,notoginsenoside R1 as the indexes in water extraction.Results The better extraction technology was adding 8 times amount of 70% ethanol,extracting for 3 times and 0.5 h for each time.Conclusion The considerable extraction rate of active components in th...
Keywords:Sanqi Zhixue Patchs  orthogonal design  ginsenoside Rg1  ginsenoside Rb1  notoginsenoside R1  
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