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成都及乐山市美沙酮门诊多次脱毒失败病人治疗脱失危险因素分析
引用本文:郑涵予,王雪,谢靓,胡泽卿. 成都及乐山市美沙酮门诊多次脱毒失败病人治疗脱失危险因素分析[J]. 中国药物依赖性杂志, 2011, 20(2): 145-148
作者姓名:郑涵予  王雪  谢靓  胡泽卿
作者单位:1. 四川大学华西基础医学与法医学院法医精神病教研室,成都,610041
2. 四川大学华西医院精神科,成都,610041
摘    要:目的:研究美沙酮维持治疗门诊多次脱毒失败病人脱失的危险因素,为有针对性地进行干预,降低美沙酮维持门诊治疗点的脱失率,有效防止复吸提供依据。方法:使用海洛因依赖相关因素调查表对四川省成都及乐山地区两个美沙酮维持治疗门诊两次以上脱毒失败的海洛因依赖者进行调查,保持每两周随访一次6,个月后将尚在维持治疗及脱失的人员分为两组,用Cox生存回归方法分析治疗脱失危险因素。结果:多因素Cox回归分析显示:戒药次数越多,最大使用量越大者脱失率越高。结论:既往戒药次数多,曾经使用毒品量较大的成瘾者容易脱失,建议门诊事先对病人进行评估,对具有危险脱失因素者进行针对性地干预,坚持随访,降低脱失率,防止复吸。

关 键 词:美沙酮维持治疗  药物滥用  脱失

INVESTIGATION AND ANALYSIS OF RELATED RISK FACTORS FOR DROP-OUT IN METHADONE OUTPATIENTS WITH MULTIPLE FAILURE IN DETOXIFICATION IN CHENGDU AND LESHAN
ZHENG Hanyu,WANG Xue,XIE Liang,HU Zeqing. INVESTIGATION AND ANALYSIS OF RELATED RISK FACTORS FOR DROP-OUT IN METHADONE OUTPATIENTS WITH MULTIPLE FAILURE IN DETOXIFICATION IN CHENGDU AND LESHAN[J]. Chinese Journal of Drug Dependence, 2011, 20(2): 145-148
Authors:ZHENG Hanyu  WANG Xue  XIE Liang  HU Zeqing
Affiliation:ZHENG Hanyu1,WANG Xue2,XIE Liang2,HU Zeqing1 1(Teaching and Research Section of Forensic Psychiatry,School of West China Preclinicaland Forensic Medicine of Sichuan University,Chengdu,610041) 2(Psychiatry Department of West China Hospital,610041)
Abstract:Objective: To study the risk factors for drop-out of methadone maintenance treatment(MMT) for conducting intervention in a targeted manner,improving retention rate of MMT and preventing drug relapse effectively.Methods:An investigation was conducted among MMT outpatients who failed in drug detoxification more than twice with a questionnaire.All the MMT outpatients on investigation were enrolled from two MMT clinics in Chengdu and Leshan.Follow-up visits were done once every other week.Six months later,the p...
Keywords:methadone maintenance treatment  drug abuse  drop-out  
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