1371例淋巴瘤临床特点及临床病理分析

目的分析淋巴瘤患者的临床特点。方法收集广西医科大学第一附属医院2003年1月1日至2010年12月31日经病理确诊为淋巴瘤的患者资料,从性别、年龄、病理类型、起病部位等方面进行总结分析。结果共收集1 371例淋巴瘤患者,非霍奇金淋巴瘤（NHL）与霍奇金淋巴瘤（HL）之比为13.28∶1,男女之比为1.87∶1。96例HL中,男女之比为2.20∶1,中位年龄28岁（3~75岁）。以混合细胞型霍奇金淋巴瘤（MCCHL）为主（占63.95%）。Ⅲ期B组占20.93%,结性起病98.84%,结外起病19.77%。1 275例NHL患者中,男女之比为1.85∶1,中位年龄47岁。NHL中以弥漫大B细胞淋巴瘤（DLBCL）为主（占49.23%）。Ⅱ期A组占18.62%,在NHL中结性起病72.36%,结外起病66.67%。结论 HL和NHL存在性别、年龄、起病部位等差别。

Analysis of pathology and clinical characteristic of 1371 patients with Lymphoma

Objective To analysis the clinical characteristics of lymphoma.Methods Clinical data of lymphoma patients from 2003 to 2010 in the first affiliated hospital of Guangxi medical university were collected and analyzed,including age,sex,pathological classification and onset locus of lymphoma and so on.Result The ratio of Non-Hodgkin′s lymphoma（NHL）to Hodgkin lymphoma（HL）was13.28 ∶1,male to female 1.87 ∶1.96 cases were HL,in which the ratio of male to female was 2.20 ∶1,the median age was 26（3-75 years）.Mixed cellularity classical Hodgkin lymphoma（63.95%） was the most common pathological type.20.93% cases belong to stage Ⅲ and B group.98.84% cases were classified as nodal lymphoma,while 19.77% classified as extranodal lymphoma.And 1275 cases were NHL in which male to female ratio was 1.85 ∶1,median age was 47（1-94 yesrs）,the most common pathological type was diffuse large B cell lymphoma（49.23%）.18.62% belong to stage Ⅲ and B group.72.36% were classified as nodal lymphoma,while 19.77% were classified as extranodal lymphoma.Conclusion There were differences between HL and NHL in the gender,age,pathological classification,onset locus and clinical staging.