| 肝硬化患者肺微循环多层螺旋CT灌注研究 |
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| 引用本文： | 薛雁山,郭志军,王新文,李红梅,田桂琴. 肝硬化患者肺微循环多层螺旋CT灌注研究[J]. 中国医学影像学杂志, 2011, 19(1): 14-18. DOI: 10.3969/j.issn.1005-5185.2011.01.004 |
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| 作者姓名： | 薛雁山 郭志军 王新文 李红梅 田桂琴 |
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| 作者单位： | 山西医科大学第二医院影像科,山西太原,030001 |
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| 摘 要： | 目的:采用MSCT灌注成像技术研究肝硬化患者肺部微循环灌注参数的变化。材料和方法:对20例正常对照组、24例代偿期肝硬化组和19例失代偿期肝硬化组行16层螺旋CT肺部同层动态增强扫描后,在工作站上使用perfusion3软件包对扫描数据进行处理,得出感兴趣区的时间-密度曲线(time-density curve,TDC)和各灌注参数值,包括血流量(blood flow,BF)、血容量(blood volume,BV)、对比剂平均通过时间(mean transit time,MTT)和表面渗透积乘积(permeability surface area product,PS)。采用SPSS11.5软件包对上述数据进行统计学分析。结果:BF、BV值在各组的总体均数差别有统计学意义(P<0.01)。失代偿期肝硬化组的BF、BV值较正常对照组和代偿期肝硬化组都明显增加,组间差别有统计学意义(P<0.01)。代偿期肝硬化组的BF、BV值与正常对照组比较,组间差别无统计学意义(P>0.05)。MTT值各组的总体均数间差别有统计学意义(0.05>P>0.01)。失代偿期肝硬化组的MTT值较正常对照组和代偿期肝硬化组减少,组间差别有统计学意义(0.05>P>0.01)。PS值各组间差别无统计学意义(P>0.05)。结论:MSCT肺部微循环灌注成像技术可反映肝硬化患者病情程度。
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| 关 键 词： | 肝硬化 微循环,肺 体层摄影术,螺旋计算机 |
Multislice CT Perfusion of Pulmonary Microcirculation on Patients with Hepatic Scerlosis |
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| XUE Yanshan,GUO Zhijun,WANG Xinwen,LI Hongmei,TIAN Guiqin. Multislice CT Perfusion of Pulmonary Microcirculation on Patients with Hepatic Scerlosis[J]. Chinese Journal of Medical Imaging, 2011, 19(1): 14-18. DOI: 10.3969/j.issn.1005-5185.2011.01.004 |
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| Authors: | XUE Yanshan GUO Zhijun WANG Xinwen LI Hongmei TIAN Guiqin |
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| Affiliation: | XUE Yanshan GUO Zhijun WANG Xinwen LI Hongmei TIAN Guiqin Department of Imaging,the 2nd Hosptial Affiliated to Shanxi Medical University,Taiyuan,Shanxi 030001 |
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| Abstract: | Purpose To study the change of perfusion parameters of pulmonary microcirculation in different severity of liver cirrhosis with multi-slice CT(MSCT).Materials and Methods Dynamic contrast-enhanced single-location sequence CT scans of the lung were obtained in 20 control subjects,24 patients with compensated cirrhosis and 19 patients with decompensated cirrhosis.These data were processed on workstation using perfusion 3 software packages.The time-density curve(TDC)of region of interest and perfusion paramete... |
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| Keywords: | liver cirrhosis microcirculation pulmonary tomography spiral computed |
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