| 氯化甲基汞对雄性小鼠的生殖毒作用 |
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| 引用本文： | 李景舜 孙长杰. 氯化甲基汞对雄性小鼠的生殖毒作用[J]. 环境与健康杂志, 1994, 11(4): 150-151 |
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| 作者姓名： | 李景舜 孙长杰 |
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| 作者单位： | 白求恩医大环境卫生教研室，白求恩医大中心实验室 |
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| 摘 要： | 以１／５０００ＬＤ５０、１／１０００ＬＤ５０和１／１００ＬＤ５０的氯化甲基汞剂量分别给雄性小白鼠经口染毒７５天后，测定睾丸组织中的ＬＰＯ和ＬＤＨ－ｘ。结果表明，实验组的ＬＰＯ高于对照组；１／１０００ＬＤ５０和１／１００ＬＤ５０组的ＬＤＨ－Ｘ均低于对照组和１／５０００ＬＤ５０组；睾丸脏器系数各组间无差别。同时探讨了甲基汞造成雄性动物生殖能力下降的可能机制。
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| 关 键 词： | 氯化甲基汞 小鼠 雄性 繁殖力 毒性 |
Toxic Effect of MeHg on Reproductive System in Male Mice |
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| Li Jing shun,Zhao Shuhua,Du Enchun. Toxic Effect of MeHg on Reproductive System in Male Mice[J]. Journal of Environment and Health, 1994, 11(4): 150-151 |
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| Authors: | Li Jing shun Zhao Shuhua Du Enchun |
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| Abstract: | Mice were administered MeHg via oral at doses of 1/5000 LD(50),1/1000LD(50) and 1/100LD(50) respectively for 75 days.The results showed that LPO of the mice treated with MeHg was higher than the control.There was marked reduce for LDH-x activity in the treated groups of 1/1000 LD(50) and 1/100 LD(50) compared with the control(P<0.05).Meanwhile,it was studied that the possible mechanism of the reproductive toxicity induced by MeHg in mice. |
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| Keywords: | MeHg LPO LDH-x |
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