Detection of antisperm-antibodies in patients with primary testicular cancer |
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Authors: | R S FOSTER L R RUBIN A MCNULTY R BIHRLE J P DONOHUE |
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Institution: | Department of Urology, Indiana University School of Medicine, Indianapolis 46202-5250. |
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Abstract: | Serum antisperm-antibodies have been noted to develop as a result of various types of testicular pathology and injury. Their presence sometimes correlates with impaired fertility. We examined 52 patients with non-seminomatous low-stage testicular cancer for the presence of serum antisperm-antibodies to determine whether or not auto-immunity is a factor in the depressed fertility known to exist in these patients. Twenty-one per cent were discovered to have serum antisperm-antibodies using an immunofluorescent technique. |
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Keywords: | antisperm-antibodies immunofluorescence testis cancer |
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