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体外诱导骨髓间充质干细胞向血管内皮细胞分化的研究
引用本文:丁洋,万圣云. 体外诱导骨髓间充质干细胞向血管内皮细胞分化的研究[J]. 医学综述, 2008, 14(7): 987-989
作者姓名:丁洋  万圣云
作者单位:安徽医科大学第一附属医院血管外科,合肥,230022
摘    要:骨髓间充质干细胞(MSCs)主要存在于骨髓中,在脐血、外周血、脂肪、皮肤等多种组织中也相继分离出MSCs。MSCs具有多向分化的能力,在一定条件下可分化为各种不同来源的细胞。目前,MSCs的分离培养、诱导分化及鉴定体系已趋成熟,其在临床应用的前景广阔。血管内皮细胞(VECs)来源于中胚层,因此MSCs具有分化为VECs的可能性。

关 键 词:骨髓间充质干细胞  内皮细胞  细胞分化
文章编号:1006-2084(2008)07-0987-03
修稿时间:2007-10-01

Differentiation of Mesenchymal Stem Cells into Vessel Endothelial Cells in Vitro
DING Yang,WAN Sheng-yun. Differentiation of Mesenchymal Stem Cells into Vessel Endothelial Cells in Vitro[J]. Medical Recapitulate, 2008, 14(7): 987-989
Authors:DING Yang  WAN Sheng-yun
Affiliation:DING Yang,WAN Sheng-yun.(Department of Vascular Surgery,First Affiliated Hospital of Anhui Medical University,Hefei 230022,China)
Abstract:Mesenchymal stem cells(MSCs)are mainly localized in the bone marrow and also are resided in the umbilical blood,peripheral blood,fatty tissue,skin,and so on.MSCs have the potential to differentiate into mesenchymal tissues in vivo and vitro.At present,the system of cultivation,induction and identification of MSCs are gradually becoming mature.Meanwhile,vessel endothelial cells derived from the mesoderm,so MSCs have potency to differentiate into vessel endothelial cells.
Keywords:Mesenchymal stem cells  Endothelial cell  Cell differentiation  
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