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Potent transmission-blocking monoclonal antibodies from naturally exposed individuals target a conserved epitope on Plasmodium falciparum Pfs230
Affiliation:1. Program in Molecular Medicine, the Hospital for Sick Children Research Institute, Toronto, ON, Canada;2. Department of Medical Microbiology, Radboudumc, Nijmegen, the Netherlands;3. TropIQ Health Sciences, Nijmegen, the Netherlands;4. Radboud Institute for Health Sciences, Department for Health Evidence, Biostatistics Section, Radboudumc, Nijmegen, the Netherlands;5. AbCellera Biologics Inc., Vancouver, BC, Canada;6. PATH''s Malaria Vaccine Initiative, Washington, DC 20001, USA;7. Infectious Disease Research Collaboration, Kampala, Uganda;8. Department of Medicine, University of California, San Francisco, San Francisco, CA, USA;9. Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA;10. Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA;11. Departments of Biochemistry and Immunology, University of Toronto, Toronto, ON, Canada
Abstract:
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  • Keywords:human monoclonal antibodies  malaria  natural infection  transmission-blocking  Pfs230
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