Monoclonal IgA J539 binds galactopyranosyl antigens on its surface |
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| Authors: | G Ekborg Y Ittah C P Glaudemans |
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| Affiliation: | National Institute of Arthritis, Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20205, USA |
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| Abstract: | Murine monoclonal IgA J539 binds to methyl beta-D-galactopyranoside. With nearly the same affinity, it binds to methyl 6-O-pivaloyl-beta-D-galactopyranoside (4) and to methyl 6-O-beta-D-gentiobiosyl-beta-D-galactopyranoside (7). These observations confirm that the combining area of J539 is of the surface-, and not of the cavity-type. |
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| Keywords: | To whom correspondence should be addressed. |
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