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中国乌头的研究 ⅩⅢ.北草乌中的生物碱
引用本文:王永高,朱元龙,朱任宏.中国乌头的研究 ⅩⅢ.北草乌中的生物碱[J].药学学报,1980,15(9):526-531.
作者姓名:王永高  朱元龙  朱任宏
作者单位:庐山植物园,中国科学院上海药物研究所,中国科学院上海药物研究所 江西庐山
摘    要:从内蒙古赤峰产的北草乌中共分得五种结晶性的生物碱,并证明其中四种为已知物,即去氧乌头碱(deoxyaconitine),次乌头碱(hypaconitine),乌头碱(aconitine)和新乌头碱(mesaconitine);另一种为新生物碱,暂称北草乌碱(beiwutine),熔点196~198℃,分子式C33H45NO12,结构式推定如图(1)。此草乌中的主要生物碱为新乌头碱。

收稿时间:1979-05-03

ALKALOIDS OF THE CHINESE DRUGS, ACONITUM SPP. XIII ALKALOIDS FROM PEI CAO WU, ACONITUM KUSNEZOFFU
Wang Yonggao Zhu Yuanlong and Zhu Renhong.ALKALOIDS OF THE CHINESE DRUGS, ACONITUM SPP. XIII ALKALOIDS FROM PEI CAO WU, ACONITUM KUSNEZOFFU[J].Acta Pharmaceutica Sinica,1980,15(9):526-531.
Authors:Wang Yonggao Zhu Yuanlong and Zhu Renhong
Abstract:Five alkaloids were isolated from the Chinese drug, Aconitum kusnezoffii collected from Ghifeng in Inner Mongolia, four of them were identified as deoxyaconitine, hypaconitine, aconitine and mesaconitine respectively by comparing their physical and chemical properties with those of authentic samples. The fifth alkaloid melting at 196~8℃ with the empirical formula G33H45NO12 was found to be a new compound. By means of interpretation of its IR and NMR spectra its structure may be suggested as Fig. I. It is named beiwutine.
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