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孕妇宫颈巨细胞病毒分离及其母婴传播的初步探讨
引用本文:郭永建,吴洁如,施凯.孕妇宫颈巨细胞病毒分离及其母婴传播的初步探讨[J].中南大学学报(医学版),1985(1).
作者姓名:郭永建  吴洁如  施凯
作者单位:湖南医学院微生物学教研室 研究生 (郭永建),湖南医学院微生物学教研室 导师 (吴洁如),湖南医学院微生物学教研室 导师(施凯)
摘    要:孕妇宫颈巨细胞病毒(CMV)排出率为4.12%(8/193)。宫颈排出CMV的母亲所分娩的6名婴儿中有4名受感染,其中1名从唾液和尿排出CMV长达7个月以上。从3名母亲的乳汁分离出CMV,其中1名特续存在1个月以上。3名从宫颈分泌物和乳汁排出CMV者,其婴儿均受到感染。结果表明CMV在母婴之间传播。

关 键 词:巨细胞病毒  包涵体  荧光抗体技术  宫颈分泌物  人乳  尿  唾液  母亲  婴儿  分离  传播

PRELIMINARY STUDY ON CERVICAL EXCRETION OF CYTOMEGALOVIRUS IN PREGNANCY AND MATERNAL-INFANT TRANSMISSION
Guo Yongjian Wu Jieru Shi Kai.PRELIMINARY STUDY ON CERVICAL EXCRETION OF CYTOMEGALOVIRUS IN PREGNANCY AND MATERNAL-INFANT TRANSMISSION[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),1985(1).
Authors:Guo Yongjian Wu Jieru Shi Kai
Institution:Guo Yongjian Wu Jieru Shi Kai Department of Microbiology,Hunan Medical College
Abstract:The cervical excretion of cytomegalovirus (CMV) was investigated in 193 pregnant women. The percentage of cervical CMV excretion was 4.12%(8/193). During the virological follow-up, of six infants born of the mothers with cervical CMV excretion, four were infected. One of them excreted CMV from saliva and urine over seven months. CMV Was isolated from the breast milk of three mothers, and persisted in a mother's milk at least for one month. Three infants whose mothers excreted CMV from both cervical secretion and breast milk were all infected.The results suggest that:(1) CMV transmission from mothers to their offsprings are relatively common; (2) mothers are the major sources of infant infection; and (3) infected cervical secretion and breast milk play an important role in perinatal transmission of CMV.
Keywords:Cytomegaloviruses Inclusion body Cervix uteri  secretion Milk  human Saliva Urine Mothers Infants Isolation Transmission Fluorescent antibody technique
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