临床药师持续性干预对我院丙氨酰谷氨酰胺使用的效果分析

目的：探讨临床药师持续性干预对我院丙氨酰谷氨酰胺注射液合理使用的作用与效果。方法：对2013年第一、二、三季度所有应用丙氨酰谷氨酰胺注射液的出院病历进行收集与分析,比较干预前后临床使用该药的变化情况。结果：持续性干预后丙氨酰谷氨酰胺注射液消耗金额占总药品消耗金额的比例为0.53%,使用率为5.80%,与干预前及第一次干预后比较,差异有统计学意义（P〈0.05）;合理使用率为91.48%,在用药适应证、溶媒选择、用药疗程等方面与干预前相比差异具有统计学意义（P〈0.05）。结论：临床药师对我院丙氨酰谷氨酰胺注射液的使用进行持续性干预,使其临床使用规范合理,表明持续性干预是可行、有效的。

Effect analysis of continuous interventions by clinical pharmacists on the rational use of alanyl glutamine

Objective： To explore the role of clinical pharmacists in the rational use of alanyl glutamine injections and evaluate the intervention effect. Methods： All the discharge medical orders using alanyl glutamine injections during the first quarter, the second quarter and the third quarter in 2013 were analyzed, and the changes of clinical application of alanyl glutamine injections before and after the intervention were compared. Results：The consumption sum of alanyl glutamine injections accounted for 0.53%of the total. The usage rate was 5.80%after the continuous intervention, the difference before and after the intervention was signiifcant （P〈0.05）. The rational usage rate was 91.48%, the differences of indications, the choice of solvents, and the course of treatment before and after the intervention were significant （P 〈 0.05）. Conclusion： The clinical usage of alanyl glutamine injections was basically reasonable after the continuous interventions by clinical pharmacists, thus the continuous interventions were very necessary and feasible.