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化疗栓塞联合质子放射治疗肝癌合并门脉主干癌栓的临床应用
引用本文:李强,曾从俊,王莺.化疗栓塞联合质子放射治疗肝癌合并门脉主干癌栓的临床应用[J].介入放射学杂志,2009,18(4).
作者姓名:李强  曾从俊  王莺
作者单位:上海交通大学医学院苏州九龙医院影像科,苏州,215021
摘    要:目的 探讨栓塞化疗联合质子放射治疗肝癌合并门脉主干癌栓的临床效果.方法 46例肝癌合并门静脉癌柃患者,接受介入栓塞化疗与质子联合治疗,将质子放射治疗分程并与介入治疗交替进行.评价其近期疗效、放射反应、随访生存率.结果 有效率91.3%,门脉癌栓消失率45.6%,肝功能恢复良好,AFP水平显著下降;放疗中或放疗后无一例发生明确的急慢性放射性肝损伤或放射性肝病;1、6个月,1、2年生存率分别为100%、89.1%、52.2%、21.4%.中位生存期17.6个月.结论 对于合并门脉癌栓形成的晚期肝癌患者,介入联合质子放射治疗是一种新的安全有效方法.

关 键 词:  肝细胞  门静脉癌栓  栓塞  治疗性  质子  放射疗法

Interventional chemoembolization combined with proton radiotherapy for the treatment of hepatocellular carcinoma accompanied with portal cancerous thrombus
LI Qiang,ZENG Cong-jun,WANG Ying.Interventional chemoembolization combined with proton radiotherapy for the treatment of hepatocellular carcinoma accompanied with portal cancerous thrombus[J].Journal of Interventional Radiology,2009,18(4).
Authors:LI Qiang  ZENG Cong-jun  WANG Ying
Institution:LI Qiang,ZENG Cong-jun,WANG Ying. Department of Radiology,Kowloon Hospital,School of Medicine,Shanghai Jiaotong University,Suzhou 215021,China
Abstract:Objective To evaluate the interventional chemoembolization combined with proton radiotherapy in the treatment of hepatocellular carcinoma (HCC) accompanied with cancerous thrombus in the main portal vein. Methods Interventional chemoembolization combined with proton radiotherapy was performed in 46 patients of HCC accompanied with cancerous thrombus in the main portal vein. The proton radiotherapy was broke up into several fractions. The patients were treated with interventional chemoembolization and, alter...
Keywords:carcinoma  hepatocellular  portal cancerous thrombus  embolization  therapeutic  proton  radiotherapy  
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