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武陵山区不同产地马比木药材中喜树碱的含量比较
引用本文:吴开慧,蔡其辉,吕江明,田宏现.武陵山区不同产地马比木药材中喜树碱的含量比较[J].中南药学,2011,9(3):197-200.
作者姓名:吴开慧  蔡其辉  吕江明  田宏现
作者单位:1. 常德市第一人民医院药剂科,湖南,常德,415000
2. 吉首大学生物资源与环境科学学院,湖南,吉首,416000
3. 吉首大学医学院,湖南,吉首,416000
摘    要:目的比较武陵山区不同产地马比木药材品质优劣。方法运用高效液相色谱(HPLC)法,采用HypersilODS2柱(250 mm×4.6 mm,5μm),流动相为乙腈-水(6∶4),检测波长为254 nm,流速为1.0 mL.min-1,柱温:20℃,以喜树碱为指标成分作比较。结果武陵山区以湖南省吉首产马比木药材中喜树碱含量明显高于其他产地样品,高达0.48%。结论该产地品系可作为中药材规模化生产的优良种质资源。

关 键 词:喜树碱  武陵山区  马比木

Camptothecine in herb of Nothapodytes Pittosporoides from different areas of Wuling mountain
WU Kai-hui,CAI Qi-hui,LV Jiang-ming,TIAN Hong-xian.Camptothecine in herb of Nothapodytes Pittosporoides from different areas of Wuling mountain[J].Central South Pharmacy,2011,9(3):197-200.
Authors:WU Kai-hui  CAI Qi-hui  LV Jiang-ming  TIAN Hong-xian
Institution:WU Kai-hui1,CAI Qi-hui2,LV Jiang-ming3,TIAN Hong-xian2(1.Department of Pharmacy,First People's Hospital of Changde,Changde Hunan 415000,2.College of Biological Resources and Environmental Science,Jishou University,Jishou Hunan 41600,3.Medicine College of Jishou University,Jishou Hunan 41600)
Abstract:Objective To compare the quality of Nothapodytes Pittosporoides herbs from different areas of Wuling mountain.Methods HPLC was used with Hypersil ODS2 column(250 mm×4.6 mm,5 μm) at 20 ℃.The mobile phase was acetonitrile-water(6∶4),the detected wavelength was 254 nm,and the flow rate was 1.0 mL·min-1.The component of camptothecine was used as index.Results The content of camptothecine in Wuling mountain Jishou Hunan was higher than other samples by 0.48%.Conclusion This strain of origin can be used as fine germplasm resources of Chinese herbal medicines for large-scale production.
Keywords:camptothecine  Wuling mountain areas  Nothapodytes Pittosporoides  
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