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急性白血病患者血清白细胞介素-6白细胞介素-8的变化
引用本文:万鼎铭. 急性白血病患者血清白细胞介素-6白细胞介素-8的变化[J]. 中国临床保健杂志, 2005, 8(2): 105-106
作者姓名:万鼎铭
作者单位:郑州大学第一附属医院血液科,450052
摘    要:目的 探讨血清IL- 6、IL -8水平变化与急性白血病(AL)发生、发展及预后的关系。方法 采用放射免疫法检测5 6例AL患者血清IL- 6、IL- 8水平,2 8例正常健康者血清IL- 6、IL- 8水平。结果 AL患者血清IL- 6、IL -8水平明显增高,完全缓解后,IL- 6、IL -8恢复正常。结论 血清IL- 6、IL- 8的异常升高在急性白血病的发生、发展中可能起一定作用,检测AL患者血清IL- 6、IL- 8水平对判断疗效、估计预后、监测复发有一定意义。

关 键 词:白血病  白细胞介素-6  白细胞介素-8  放射免疫测定
文章编号:1672-6790(2005)02-0105-02
修稿时间:2004-01-05

Study on serum level of IL-6 and I-8 in patient with acute leukemia
WAN Dingming. Study on serum level of IL-6 and I-8 in patient with acute leukemia[J]. Chinese Journal of Clinical Healthcare, 2005, 8(2): 105-106
Authors:WAN Dingming
Abstract:Objective To explore the rela ti onship between serum levels of IL-6 and IL-8 with the development progress and p rognosis in patients with cute leukemia.Methods To measure the serum level of IL-6 and IL-8 in 56 patients with acute lymphoblastic leukemia and 28 normal subjects by radioimmunoassay.Results The serum le vel of IL-6 and IL-8 in patients with acute leukemia was higher than those in control group,which can be restored after complete remission.Conclusions The higher serum level of IL-6 and IL-8 in acute leukemia is probabl y related to development,progress,and they is useful to judge efficacy,estimate prognosis and mornitor relapse of acute leukemia.
Keywords:Leukemia  Interleukin-6(IL-6)  Interleukin-8(IL -8)  Radioimmunoassay
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