| 紫外分光光度法测定兔血清中二氯乙酸钠浓度 |
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| 引用本文： | 蒋永培,顾斌.紫外分光光度法测定兔血清中二氯乙酸钠浓度[J].第四军医大学学报,1994,15(4):300-302. |
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| 作者姓名： | 蒋永培 顾斌 |
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| 作者单位： | 西京医院药品制剂科 |
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| 摘 要： | 作建立检测二氯乙酸钠血清浓度的紫外分光光度法，平均回收率为１０１．４％，日内变异为３．３％，日间变异为３．８％，最低检测浓度为１ｍｇ／Ｌ。应用本法研究二氯乙酸钠（ｉｖ，１８０ｍｇ／ｋｇ）在兔体内的药代动力学，主要药代动力学参数为：Ｔ１／２＝０．６７ｈ，Ｖｄ＝０．２８Ｌ／ｋｇ，Ｋ＝１．１ｈ＾－１，Ｃｌ＝０．３１Ｌ／ｋｇ／ｈ，ＡＵＣ＝６０５．１ｍｇ．ｈ／Ｌ。
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| 关 键 词： | 分光光度法 二氧乙酸钠 血清 |
Determination of serum sodium dichloroacetate content in rabbits us-ing ultraviolet spectrophotometry |
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| JIANG Yong-Pei,GU Bin,WANG Ji-Bao,WENG Ai-Dong and SONG Lin.Determination of serum sodium dichloroacetate content in rabbits us-ing ultraviolet spectrophotometry[J].Journal of the Fourth Military Medical University,1994,15(4):300-302. |
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| Authors: | JIANG Yong-Pei GU Bin WANG Ji-Bao WENG Ai-Dong and SONG Lin |
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| Institution: | JIANG Yong-Pei,GU Bin,WANG Ji-Bao,WENG Ai-Dong and SONG LinDepartment of Pharmacy,Xijing Hospital |
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| Abstract: | |
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| Keywords: | ultraviolet spectrophotometry sodium dichloroacetate serum |
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