清凉活化散载药护膝治疗急性期膝骨性关节炎的疗效观察

目的研究清凉活化散载药护膝对急性期膝骨性关节炎的临床疗效。方法入组患者300例,随机分为弹力绷带组、扶他林组与载药护膝组,每组100例。三组均予基础治疗与基础护理。扶他林组予扶他林乳膏外涂;弹力绷带组、载药护膝组予清凉活化散外敷,并分别用弹力绷带、载药护膝固定。观察压痛、肿胀、关节炎指数、生活质量等指标,并进行疗效评价。结果载药护膝组的压痛积分、疼痛积分与弹力绑带组比较,差异有统计学意义(P均0.05),载药护膝组、弹力绷带组的肿胀积分、生活质量PF、RP、BP、GH积分与扶他林组比较,差异有统计学意义(P0.01或P0.05),载药护膝组的活动度积分、关节炎指数与弹力绷带组、扶他林组比较,差异有统计学意义(P0.01或P0.05)。三组依从率均为100%。载药护膝组皮疹发生率与弹力绷带组比较,差异有统计学意义(P0.01)。载药护膝组总满意率与弹力绷带组比较,差异有统计学意义(P0.05)。载药护膝组、弹力绷带组总有效率与扶他林组比较,差异有统计学意义(P均0.01)。结论与弹力绷带组、扶他林组比较,载药护膝组在症状改善、疗效等方面,或维持原有优势,或得到明显提高,基本实现改良预期,将有助于清凉活化散的临床推广。

Effectiveness of drug carrying kneecap of Qinglianghuohua powder on acute knee osteoarthritis

Objective To investigate the effectiveness of drug carrying kneecap of Qinglianghuohua powder on the acute knee osteoarthritis.Methods A total of 300 patients were selected and randomized into pressure bandage group,Voltaren group and drug carrying kneecap group with 100 patients in each.All the patients were given basic treatment and nursing care.Patients in Voltaren group were treated with external application of Voltaren paste.Patients in pressure bandage group and drug carrying kneecap group were treated with external application of Qinglianghuohua powder and fixed with pressure bandage and drug carrying kneecap respectively.Tenderness,swelling,arthritis index and life quality were observed and the effectiveness was evaluated.Results Scores of tenderness and pain in drug carrying kneecap group were statistically different from those in pressure bandage group(P all<0.05).From those in Voltaren group,scores of swelling,PF,RP,BP and GH scores of life quality in drug carrying kneecap group and pressure bandage group were statistically different(P<0.01 or P<0.05).Activity score and arthritis index in drug carrying kneecap were statistically different from those in pressure bandage group and Voltaren group(P<0.01 or P<0.05).Compliance rates of three groups were 100%.The incidence of rash in drug carrying kneecap group was statistically different from that of pressure bandage group(P<0.01).Total satisfactory rate of drug carrying kneecap group was statistically different from that of pressure bandage group(P<0.05).Total rates of effectiveness in drug carrying kneecap group and pressure bandage group were statistically different from that of Voltaren group(P all<0.01).Conclusion Compared with pressure bandage group and Voltaren group,drug carrying kneecap group maintained or significantly improved the original advantage in the aspects of symptom improvement and effectiveness.The expectation of improvement is basically actualized,which is helpful for the clinical promotion of Qinglianghuohua powder.