Nutrition therapy for diabetic gastroparesis |
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Authors: | Diana Gentilcore Deirdre O'Donovan Karen L. Jones Michael Horowitz |
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Affiliation: | (1) Department of Medicine, Royal Adelaide Hospital, North Terrace, 5000 Adelaide, South Australia, Australia |
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Abstract: | The management of diabetic gastroparesis often represents a significant clinical challenge in which the maintenance of nutrition is pivotal. Gastric emptying is delayed in 30% to 50% of patients with longstanding type 1 or type 2 diabetes and upper gastrointestinal symptoms also occur frequently. However, there is only a weak association between the presence of symptoms and delayed gastric emptying. Acute changes in blood glucose concentrations affect gastric motility in diabetes; hyperglycemia slows gastric emptying whereas hypoglycemia may accelerate it; blood glucose concentrations may also influence symptoms. It is now recognized that gastric emptying is a major determinant of postprandial glycemia and, therefore, there is considerable interest in the concept of modulating gastric emptying, by dietary or pharmacologic means, to optimize glycemic control in diabetes. |
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