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进驻海拔5,380m不同时间的青年人血液流变性和RBC—SOD的变化
引用本文:张西洲,何富文.进驻海拔5,380m不同时间的青年人血液流变性和RBC—SOD的变化[J].西藏医药杂志,1997,18(3):8-10.
作者姓名:张西洲  何富文
作者单位:解放军第18医院
摘    要:本文对进驻海拔5,380m第3天、第25天、第4个月,第11个月的20名青年血液流变性和RBC-SOD进行了随访调查,并与进驻高原前作对照,结果:随进驻高原时间的延续,HCT、ηb、PFc、TK、MST、TFL递增,RBC-SOD递减(P<0.01或P<0.05)。作者认为缺氧引起HCT增高是血液粘度增高的重要因素;缺氧引起ATP生成减少和红细胞内液粘度增高是红细胞变形能力降低的主要原因。高原低氧环境使体内自由基生成增多,SOD活性降低。

关 键 词:高原  血液流变学  超氧化物歧化酶

The change of blood rheological property and RBC-SOD on youth who are garrisoned to regions 5380m above sea level at different time
Zhang Xizhou, He Fuwen, ZhangXinyu, Wang Wei, Ma Yong, Zhang SupIng,.The change of blood rheological property and RBC-SOD on youth who are garrisoned to regions 5380m above sea level at different time[J].Tibetan Medical Journal,1997,18(3):8-10.
Authors:Zhang Xizhou  He Fuwen  ZhangXinyu  Wang Wei  Ma Yong  Zhang SupIng  
Institution:The 18th Hospital of PLA
Abstract:Follow - up survey of blood rheological property and RBC-SOD were made among 20 young people who are garrisoned to regions 5380m above sea level on the 3rd day, the 25th day, the 4th month, the 11thmonth; and compared with those records before garrison. The result shows that following the garrison time prolonged in altitude,HCT. 3b. PFC. TK. MST. TFL increased progressively, RBC - SOD decreaseu progressively (p < 0.01 or p <0.05 ). The writer considers that increasilig of HCT cau sed by hypoxia is an important factor ofblood viscosity increasing; ATP formation decreasing and internal fluid viscosity of RBC increasing caused by hypoxia is the main cause of decreasing of RBC distortion ability;altitude hypoxia environment caused inner - body free radical formation increasing and SOD activity decreasing.
Keywords:altitude  blood rheology  superoxide dismutase
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