| 白血病细胞促凝活性的研究 |
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| 引用本文： | 姚尔固,李玉秀. 白血病细胞促凝活性的研究[J]. 河北医科大学学报, 1986, 0(2) |
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| 作者姓名： | 姚尔固 李玉秀 |
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| 作者单位： | 河北医学院附属二院血液病研究室，河北医学院附属二院血液病研究室 |
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| 摘 要： | 本文检测34例急性白血病完整与破碎白血病细胞的促凝活性。26例急性非淋巴细胞白血病(ANLL)均无弥散性血管内凝血(DiC)依据,其完整白血病细胞的促凝活性增加,尤以M_5型为明显,而8例急性淋巴细胞白血病的完整白细胞均无促凝活性。破碎白血病细胞均无促凝活性。我们认为用细胞毒药物快速破坏白血病细胞仍是有效防止DIC的措施之一,若合用肝素可能更好。
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| 关 键 词： | 凝血酶致活酶 代谢 血细胞 酶学 白血病 酶学 人类 |
STUDY ON THE CELLULAR PROCOAGULANT ACTIVITY IN LEUKEMIA |
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| Yao Ergu Li Yushiu Research. STUDY ON THE CELLULAR PROCOAGULANT ACTIVITY IN LEUKEMIA[J]. Journal of Hebei Medical University, 1986, 0(2) |
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| Authors: | Yao Ergu Li Yushiu Research |
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| Affiliation: | Yao Ergu Li Yushiu Research Department of Hematology,the Second Affiliated Hospital |
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| Abstract: | The cellular procoagulant activity(CPA) of the intact and lysed leukemic cells was evaluated in 34 cases of acute leukemia.The intact leukmic cells of 26 patients with acute non-lymphocytic leukmia(ANLL) without disseminated intravascular coagulation(DIC) feature showed an increase of CPA, mostly prominent in M5 subtype, while those from 8 cases of acute lymphocytic leukemia did not.The lysed leukemic cells did not show increase in CPA.Based on the results we suggest that the rapid destruction of the leukemic cells by cytotoxic agents still remains one of the effective approaches to prevent DIC in ANLL and to combine with heparin seems to be all the better. |
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| Keywords: | thromboplastin metabolism blood cells enzyzmology leukemia enzymology human |
| 本文献已被 CNKI 等数据库收录！ |
