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荠菜的抗炎药理作用研究
引用本文:岳兴如,田敏,徐持华,阮耀.荠菜的抗炎药理作用研究[J].时珍国医国药,2006,17(5):F0003-F0004.
作者姓名:岳兴如  田敏  徐持华  阮耀
作者单位:河南南阳医学高等专科学校,河南,南阳,473000
摘    要:目的研究荠菜抗炎药理作用。方法分别用二甲苯致小鼠耳肿胀,冰醋酸致小鼠腹腔毛细血管通透性增加及小鼠扭体反应,酵母多糖A、角叉菜胶、制霉菌素致大鼠或小鼠足趾肿胀模型,ig给药,观察荠菜的抗炎作用。结果荠菜能减轻二甲苯所致小鼠耳肿胀、冰醋酸所致小鼠腹腔毛细血管通透性增加,角叉菜胶、酵母多糖A所致大鼠足趾肿胀,但对制霉菌素所致的炎症模型无明显作用。结论荠菜具有一定的抗炎作用,其机理涉及对多种炎症介质的抑制,抗炎作用能部分解释荠菜生药的传统功效。

关 键 词:荠菜  抗炎
文章编号:1008-0805(2006)05-封3-02
收稿时间:2005-07-11
修稿时间:2006-02-23

Studies on Anti - inflammatory Effect of Capsellae bursa -pastoris
YUE Xing-ru,TIAN Min,XU Chi-hua,RUAN Yao.Studies on Anti - inflammatory Effect of Capsellae bursa -pastoris[J].Lishizhen Medicine and Materia Medica Research,2006,17(5):F0003-F0004.
Authors:YUE Xing-ru  TIAN Min  XU Chi-hua  RUAN Yao
Institution:Department of Pharmacology, Nanyang Higher Medical College, Nanyang 473000, China
Abstract:ObjectiveTo study the anti-inflammatory effect of Capsellae bursa-pastoris.MethodsThe models of auricular edema in mice induced by dimethyl benzene,increased permeability of celiac blood capillary and body-twisting reaction induced by acetic acid,pawswelling induced by zymosan A,carrageenan and mystatin in rats or in mice were prepared.Then Capsellae Bursa-pastoris was given to the rats or mice by ig.ResultsCapsellae bursa-pastoris inhibited the auricular edema,decreased the permeability of celiac blood capillary,reduced the paw swelling induced by carrageenan and zymosan A,but not by nystation.Conclusion Capsellae bursa-pastoris exhibits obvious anti-inflammatory effects.
Keywords:Capsellae bursa-pastoris  Anti-inflammation  
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