| 兔肝脏保存─再灌注损伤模型的建立及评价 |
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| 引用本文： | 汤礼军,田伏洲,王雨,黄大熔,周树,胡建中.兔肝脏保存─再灌注损伤模型的建立及评价[J].肝胆外科杂志,1998(2). |
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| 作者姓名： | 汤礼军 田伏洲 王雨 黄大熔 周树 胡建中 |
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| 作者单位： | 成都军区总医院全军普外中心实验室!成都，610083，成都军区总医院全军普外中心实验室!成都，610083，成都军区总医院全军普外中心实验室!成都，610083，成都军区总医院全军普外中心实验室!成都，610083，成都军区总医院全军普外中心实验室!成都，610083，成都军区总医院全军普外中心实验 |
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| 摘 要： | 作者应用导管将受体腹主动脉血液分流至供肝，建立了兔肝脏保存一再灌注损伤模型。并对再灌注前、后供肝及受体肝脏的组织结构及功能、再灌注后供肝血流量及受体血流动力学变化进行了动态观察。结果表明，该模型具有良好的稳定性及重复性，且能准确地反映肝移植时供肝保存一再灌注损伤的病理生理过程。
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| 关 键 词： | 兔 肝脏 保存再灌注损伤 模型 |
FOUNDATION AND EVALUTION OF A LIVER PRESERVATION REPERFUSION INJURY MODEL IN RABBITS |
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| Tang Lijun,Tian Fuzhou,Wang Yu,et al..FOUNDATION AND EVALUTION OF A LIVER PRESERVATION REPERFUSION INJURY MODEL IN RABBITS[J].Journal of Hepatobiliary Surgery,1998(2). |
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| Authors: | Tang Lijun Tian Fuzhou Wang Yu |
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| Abstract: | The rabbit liver preservation - reperfusion injury model was founded by shunting the blood of recipient's abdominal aorta to donor liv-ers. In the process of experiment,histomorphDlogical changes of pre- post - reperfusive livers of donors and recipients , blood flow of donor livers andhemodynamic changes of recipients were sequentially observed. The results suggested that the model can accurately reflect pathophysiological changes of donor liver preservation - reperfusion injury during liver transplantation. |
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| Keywords: | rabbit liver preservation-reperfusion injury model |
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