武威市消化道疾病患者幽门螺杆菌感染分析

目的了解甘肃省武威市胃肠道疾病患者组织中幽门螺杆菌(H.pylori,Hp)的感染状况。方法用Warthin-Starry银染色法结合革兰染色法判断所选组织幽门螺杆菌的感染状况。比较不同病变类型、性别、部位及不同病理类型的肿瘤组织中幽门螺杆菌的感染状况。结果胃癌组、癌前病变组和慢性浅表性胃炎组幽门螺杆菌感染率分别为86.42%(70/81)、94.12%(64/68)和80.36%(45/56),后两者比较,差异有统计学意义(P<0.05)。不同性别的病变组织间、不同部位以及不同病理类型的肿瘤组织中幽门螺杆菌的感染差异均无统计学意义。结论甘肃省武威市胃肠道疾病患者中存在较高的幽门螺杆菌感染率;幽门螺杆菌感染与性别无关;幽门螺杆菌在该地区的致癌作用与感染部位及所致胃癌的组织类型无关。

Analysis of Helicobacter pylori infection among people with upper gastrointestinal disease In Wuwei,Gansu province

ObjectiveTo study and analyze the status of Helicobacter pylori(H.pylori)infection among people suffered from upper gastrointestinal disease in Wuwei area of Gansu province.MethodsThe status of H.pylori infection of all samples were detected by Warthin-Starry and Gram stain.H.pylori infection rates of different pathological type,sex as well as the tumor tissue in different site and different pathological type were compared.ResultsThe rate of H.pylori infection in gastric carcinoma group,gastric precancerous lesions group and chronic super ficial gastritis group was 86.42% (70/81),94.12% (64/68)and 80.36% (45/56),respectively.The positive rate of H.pylori infection was significantly hig herin gastric precancerous lesions group than that of in chronic superficial gastritis group(P<0.05).There was no significant difference in H.pylori infection rate between sex as well as the tumor tissue in different site and different pathological type.ConclusionThere is a high H.pylori infection rate among people suffered from upper gastro intestinal disease in Wuwei area.H.pylori infection does not related with sex.The carcinogenic effect of H.pylori has no relation with the infection site and the patho-logical type of gastric carcinoma.